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Catalog Number Size Price
LS-C93915-100 100 µl $393 
Antibody

Polyclonal Rabbit anti‑Mouse ACCN1 / ASIC2 Antibody (aa350‑400, IHC, WB) LS‑C93915

Polyclonal Rabbit anti‑Mouse ACCN1 / ASIC2 Antibody (aa350‑400, IHC, WB) LS‑C93915

Antibody:
ACCN1 / ASIC2 Rabbit anti-Mouse Polyclonal (aa350-400) Antibody
Application:
IHC, WB
Reactivity:
Mouse, Human, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$393
LS-C93915-100
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
ACCN1 / ASIC2 Rabbit anti-Mouse Polyclonal (aa350-400) Antibody
Application:
IHC, WB
Reactivity:
Mouse, Human, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
ASIC2 antibody LS-C93915 is an unconjugated rabbit polyclonal antibody to ASIC2 (ACCN1) (aa350-400) from mouse. It is reactive with human, mouse and rat. Validated for IHC and WB. Cited in 6 publications.
Target
Mouse ACCN1 / ASIC2
Synonyms
ASIC2 | ACCN1 | ASIC2a | Brain sodium channel 1 | Degenerin | ACCN | Acid-sensing ion channel 2 | Mammalian degenerin homolog | MDEG | MDEG1 | MDEG2 | HBNaC1 | BNaC1 | MAMMALIAN DEGENERIN | ASIC2b
Host
Rabbit
Reactivity
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Immunogen
Synthetic peptide from the extracellular domain of mouse amiloride sensitive cation channel 1, neuronal (ACCN1, ASIC2) conjugated to an immunogenic carrier protein. The antigen is homologous in human and rat.
Epitope
aa350-400
Specificity
Specific for ACCN1.
Applications
  • IHC
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
IHC: Antigen retrieval is essential for use on paraffin sections.
Presentation
Lyophilized
Reconstitution
Reconstitute the lyophilized product in sterile water.
Storage
Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2°C to 8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ACCN1 / ASIC2
Q16515 NM_183377 NP_899233.1

LSBio Ratings

ACCN1 / ASIC2 Antibody (aa350-400) for IHC, WB/Western LS-C93915 has an LSBio Rating of
Publications (4.5)

Publications (6)

Regulation of acid-sensing ion channel 1a function by tissue kallikrein may be through channel cleavage. Jingjing Su, Yuping Tang, Ling Liu, Houguang Zhou, Qiang Dong. Neuroscience letters. 2011 490:46-51. (WB; Human, Hamster)

Immunohistochemical Detection of the Putative Mechanoproteins ASIC2 and TRPV4 in Avian Herbst Sensory Corpuscles. Cabo R, Gálvez A, Laurà R, San José I, Pastor JF, López-Muñiz A, García-Suárez O, Vega JA. Anatomical record (Hoboken, N.J. : 2007). 2013 296:117-22. (IHC-P; Pigeon)

The sensory innervation of the human pharynx: searching for mechanoreceptors. de Carlos F, Cobo J, Mac[Character ed]as E, Feito J, Cobo T, Calavia MG, Garc[Character ed]a-Su[Character e1]rez O, Vega JA. Anatomical record (Hoboken, N.J. : 2007). 2013 Nov;296:1735-46.

Acid-sensing ion channel 2 (ASIC2) in the intestine of adult zebrafish. Levanti MB, Guerrera MC, Calavia MG, Ciriaco E, Montalbano G, Cobo J, German[Character e0] A, Vega JA. Neuroscience letters. 2011 Apr;494:24-8.

Immunohistochemical localization of acid-sensing ion channel 2 (ASIC2) in cutaneous Meissner and Pacinian corpuscles of Macaca fascicularis. Cabo R, G[Character e1]lvez MA, San Jos[Character e9] I, Laur[Character e0] R, L[Character f3]pez-Mu[Character f1]iz A, Garc[Character ed]a-Su[Character e1]rez O, Cobo T, Insausti R, Vega JA. Neuroscience letters. 2012 May;516:197-201.

ASIC2 is present in human mechanosensory neurons of the dorsal root ganglia and in mechanoreceptors of the glabrous skin. Cabo R, Alonso P, Vi[Character f1]a E, V[Character e1]zquez G, Gago A, Feito J, P[Character e9]rez-Molt[Character f3] FJ, Garc[Character ed]a-Su[Character e1]rez O, Vega JA. Histochemistry and cell biology. Mar;143:267-76.

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Requested From: United States
Date Requested: 11/22/2024