Human ATM

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

Unconjugated

Protein G purified

Unmodified

GST fusion protein expressed in E. coli corresponding to aa 2577-3056 of full-length ATM.

aa2577-3056

Recognizes full-length ATM, a 370 kD nuclear phosphoprotein, which is involved in the autosomal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigations.

• Western blot
• Immunoprecipitation (1 - 10 µg/ml)

PBS, pH 7.4

Store at -70°C, avoid freeze/thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q13315 NCBI: NM_000051 NP_000042.3