Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-C74520-100 | 100 µg | $941 |
Monoclonal Mouse anti‑Human BACE1 / BACE Antibody (WB) LS‑C74520
Monoclonal Mouse anti‑Human BACE1 / BACE Antibody (WB) LS‑C74520
Antibody:
BACE1 / BACE Mouse anti-Human Monoclonal Antibody
Application:
WB, IP, ELISA, Neut
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
BACE1 / BACE Mouse anti-Human Monoclonal Antibody
Application:
WB, IP, ELISA, Neut
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
BACE antibody LS-C74520 is an unconjugated mouse monoclonal antibody to BACE (BACE1) from human. It is reactive with human and mouse. Validated for ELISA, IP, Neut and WB.
Target
Human BACE1 / BACE
Synonyms
BACE1 | APP beta-secretase | Asp 2 | ASP2 | Aspartyl protease 2 | Aspartylprotease 2 | Beta-secretase | Beta-site APP-cleaving enzyme | BACE | HSPC104 | KIAA1149 | B-Secretase | Beta-secretase 1 | Memapsin-2
Host
Mouse
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
NS0-derived rhBACE-1 ectodomain.
Specificity
Recognizes human BACE-1 ectodomain. Species cross-reactivity: Mouse.
Applications
- Western blot
- Immunoprecipitation
- ELISA
- Neutralization
Usage
Suitable for use in ELISA, Immunoprecipitation/ Western Blot and Neutralization. The enzyme was then assayed with a peptide substrate. 50% of the proteolytic activity was inhibited by the antibody at 10 ug/ml (IC50) under conditions in which the enzyme was present at 10 ug/ml and the substrate concentration was 10uM. Considering the molecular masses of the enzyme (75kD) and the antibody (150kD), IC50 was achieved at ~0.5:1 molar ratio of the antibody to the enzyme. Did not inhibit rhCathepsin D activity under the same conditions.
Presentation
Lyophilized PBS, pH 7.4, 5% Trehalose
Reconstitution
Reconstitute in sterile PBS.
Storage
Lyophilized and resuspended forms: store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BACE1 / BACE
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Rat
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
