Target
Human BIRC2 / cIAP1
Synonyms
BIRC2 | API1 | C-IAP1 | CIAP1 | Hiap-2 | IAP homolog B | HIAP2 | IAP-2 | RNF48 | Apoptosis inhibitor 1 | IAP2 | MIHB | RING finger protein 48
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Immunogen
A synthetic peptide corresponding to amino acids 158-175 (PNPLNSRAVEDISSSRTN) of human cIAP1, GenBank no. gi|2497238. Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Orangutan (94%); Gibbon, Monkey (89%); Marmoset, Pig (83%); Mouse, Rat (61%).
Specificity
CIAP1 has 618 amino acids and migrates at ~70 kD on SDS-PAGE. Observed molecular weights may vary as genes generally produce, by alternative splicing, multiple transcripts all with introns, putatively encoding multiple different protein isoforms. Additionally, proteins may undergo post translational modifications including phosphorylation, glycosylation and cleavage which can result in differential molecular weights. Protein modifications can vary between cell and tissue type, and proteins can migrate as one or multiple bands depending on the isoform expressed as well as post-translational modifications.
Applications
- IHC
- IHC - Paraffin (1:1000 - 1:5000)
- IHC - Frozen
- Western blot (1:1000 - 1:2000)
- Immunoprecipitation (1:50 - 1:200)
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Presentation
Antiserum, 0.05% sodium azide
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee