Human CD2

Mouse

Human (tested or 100% immunogen sequence identity)

IgG2a,k Monoclonal

1E7E8.G4

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified.

Human Thymocytes/Sezary T cells were used as the immunogen for this CD2 antibody.

Human CD2

• IHC
• IHC - Frozen
• Immunofluorescence (0.5 - 1 µg/ml)
• Western blot
• Immunoprecipitation
• Flow Cytometry (0.5 - 1 µg/10E6 cells)
• ELISA
• Functional Assay

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells. ELISA: Order BSA-free format for coating.

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P06729 NCBI: NM_001767 NP_001758.2