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| Catalog Number | Size | Price |
|---|---|---|
| LS-C338364-100 | 100 µl (1 mg/ml) | $434 |
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2 of 2
Monoclonal Mouse anti‑Human CD274 / B7‑H1 / PD‑L1 Antibody (clone OTI2C7, IF, WB) LS‑C338364
Monoclonal Mouse anti‑Human CD274 / B7‑H1 / PD‑L1 Antibody (clone OTI2C7, IF, WB) LS‑C338364
Antibody:
CD274 / B7-H1 / PD-L1 Mouse anti-Human Monoclonal (OTI2C7) Antibody
Application:
IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CD274 / B7-H1 / PD-L1 Mouse anti-Human Monoclonal (OTI2C7) Antibody
Application:
IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
PD-L1 antibody LS-C338364 is an unconjugated mouse monoclonal antibody to human PD-L1 (CD274 / B7-H1). Validated for IF and WB. Cited in 3 publications.
Target
Human CD274 / B7-H1 / PD-L1
Synonyms
CD274 | B7-H | B7 homolog 1 | B7-H1 | B7H1 | CD274 molecule | CD274 antigen | PDCD1 ligand 1 | PDL1 | PD-L1 | PDCD1L1 | PDCD1LG1 | Programmed death ligand 1
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse
Clonality
IgG1
Monoclonal
Clone
OTI2C7
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified.
Also available Carrier-free.
Immunogen
Full length human recombinant protein of human CD274(NP_054862) produced in HEK293T cell.
Specificity
Human B7-H1 / PD-L1 / CD274
Applications
- Immunofluorescence (1:100)
- Western blot (1:200 - 1:2000)
Presentation
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CD274 / B7-H1 / PD-L1
LSBio Ratings
CD274 / B7-H1 / PD-L1 Antibody (clone OTI2C7) for IF/Immunofluorescence, WB/Western LS-C338364 has an LSBio Rating of
Publications (4.2)
Learn more about The LSBio Ratings Algorithm
Publications (3)
Juxtacrine Signaling Inhibits Antitumor Immunity by Upregulating PD-L1 Expression. Wen-Hao Yang, Jong-Ho Cha, Weiya Xia, Heng-Huan Lee, Li-Chuan Chan, Ying-Nai Wang, Jennifer L Hsu, Guoxin Ren, Mien-Chie Hung. Cancer research. 2018 July;78:3761-3768.
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Junwei Hou, Rongce Zhao, Weiya Xia, Chiung-Wen Chang, Yun You, Jung-Mao Hsu, Lei Nie, Yeh Chen, Yu-Chuan Wang, Chunxiao Liu, Wei-Jan Wang, Yun Wu, Baozhen Ke, Jennifer L Hsu, Kebin Huang, Zu Ye, Yi Yang, Xianghou Xia, Yintao Li, Chia-Wei Li, Bin Shao, John A Tainer, Mien-Chie Hung. Nature cell biology. 2020 October;22:1264-1275.
Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L110<sup> Department of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA12<sup> Department of Breast Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA14<sup> Department of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate School of Biomedical Sciences. Jong-Ho Cha, Wen-Hao Yang, Weiya Xia, Yongkun Wei, Li-Chuan Chan, Seung-Oe Lim, Chia-Wei Li, Taewan Kim, Shih-Shin Chang, Heng-Huan Lee, Jennifer L Hsu, Hung-Ling Wang, Chu-Wei Kuo, Wei-Chao Chang, Sirwan Hadad, Colin A Purdie, Aaron M McCoy, Shirong Cai, Yizheng Tu, Jennifer K Litton, Elizabeth A Mittendorf, Stacy L Moulder, William F Symmans, Alastair M Thompson, Helen Piwnica-Worms, Chung-Hsuan Chen, Kay-Hooi Khoo, Mien-Chie Hung. Molecular cell. 2018 Aug;71:606-620.e7.
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Featured Products
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Flow Cytometry
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Mouse
Applications:
IHC, IHC - Frozen, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/23/2024
Date Requested: 11/23/2024
