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Catalog Number Size Price
LS-C389015-100 100 µg $575 
CDH3 / P-Cadherin Antibody - IHC-P: P-Cadherin antibody testing of human placenta tissue
CDH3 / P-Cadherin Antibody - ICC testing of P-Cadherin antibody and A549 cells
CDH3 / P-Cadherin Antibody - Western blot testing of P-Cadherin antibody and Lane 1: recombinant human protein 10ng; 2: 5ng
CDH3 / P-Cadherin Antibody - IHC-P: P-Cadherin antibody testing of human placenta tissue
CDH3 / P-Cadherin Antibody - ICC testing of P-Cadherin antibody and A549 cells
CDH3 / P-Cadherin Antibody - Western blot testing of P-Cadherin antibody and Lane 1: recombinant human protein 10ng; 2: 5ng
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Polyclonal Rabbit anti‑Human CDH3 / P‑Cadherin Antibody (aa612‑626, IHC, WB) LS‑C389015

Polyclonal Rabbit anti‑Human CDH3 / P‑Cadherin Antibody (aa612‑626, IHC, WB) LS‑C389015

Antibody:
CDH3 / P-Cadherin Rabbit anti-Human Polyclonal (aa612-626) Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human, Horse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$575
LS-C389015-100
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
CDH3 / P-Cadherin Rabbit anti-Human Polyclonal (aa612-626) Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human, Horse
Format:
Unconjugated, Unmodified

Specifications

Description
P-Cadherin antibody LS-C389015 is an unconjugated rabbit polyclonal antibody to P-Cadherin (CDH3) (aa612-626) from human. It is reactive with human and horse. Validated for ICC, IHC and WB.
Target
Human CDH3 / P-Cadherin
Synonyms
CDH3 | Cadherin-3 | HJMD | P-cadherin | CDHP | PCAD | Placental cadherin
Host
Rabbit
Reactivity
Human, Horse (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bat, Dog, Hamster, Sheep (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Amino acids 612-626 (QDTYDVHLSLSDHGN-human) were used as the immunogen for this P-Cadherin antibody. Percent identity by BLAST analysis: Human, Elephant, Horse (100%); Mouse, Rat, Sheep, Cat, Bat, Hamster, Dog (93%); Rabbit, Guinea pig (87%); Ferret, Bovine (80%).
Epitope
aa612-626
Specificity
Human CDH3 / P-Cadherin
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • ICC (0.5 - 1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. P-Cadherin is a protein that in humans is encoded by the CDH3 gene. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CDH3 / P-Cadherin
P22223 NM_001793 NP_001784.2

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Requested From: United States
Date Requested: 12/22/2024