Target
Human CYBB / NOX2 / gp91phox
Synonyms
CYBB | Chronic granulomatous disease | CGD91-phox | Cytochrome b558 subunit beta | Cytochrome b(558) subunit beta | gp91-1 | gp91-PHOX | p22 phagocyte B-cytochrome | AMCBX2 | CGD | Cytochrome b-245 heavy chain | gp91PHOX | NADPH oxidase 2 | NOX2 | p91-PHOX
Reactivity
Human, Monkey, Mouse, Rat, Bat
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated.
Also available conjugated with
APC,
Biotin,
FITC,
HRP,
PE.
Immunogen
Synthetic peptide corresponding to aa548-560 of human gp91-phox (KQSISNSESGPRG) (KLH-conjugated). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat (100%); Elephant, Panda, Dog (92%); Dolphin, Bovine, Horse, Turkey, Chicken, Platypus (85%).
Specificity
Recognizes human gp91 phox, Mr 75kD. Depending on the type of lysate, the amount loaded, the gel and the blot conditions, gp91 phox may run as a sharp band, Mr ~75kD, or appear as a smear between 75-91kD. Species sequence Homology: mouse-100%; bovine-11/13; porcine-10/13.