Target
Human FOLH1 / PSMA
Synonyms
FOLH1 | Folate hydrolase 1 | GCPII | Glutamate carboxypeptidase II | Folate hydrolase | GCP2 | NAALAD1 | NAALAdase | NAALADase I | PSM | FGCP | FOLH | Glutamate carboxylase II | Glutamate carboxypeptidase 2 | MGCP | PSMA
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated.
Also available conjugated with
PE.
Purification
Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.
Immunogen
Amino acids 44-750 of human GCPII.
Specificity
The antibody GCP-05 recognizes extracellular domain (preferentially in native form) of glutamate carboxypeptidase II (NAALADase, FOLH1, PSMA), an approximately 95-110 kDa transmembrane glycoprotein expressed mainly in tumour neovasculatures, nervous system and jejunum, which is an important prostate tumour marker.