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| Catalog Number | Size | Price |
|---|---|---|
| LS-C357743-20 | 20 µg (0.2 mg/ml) | $371 |
| LS-C357743-100 | 100 µg (0.2 mg/ml) | $574 |
Monoclonal Rat anti‑Mouse ITGAM / CD11b Antibody (clone M1/70, IHC, IF) LS‑C357743
Monoclonal Rat anti‑Mouse ITGAM / CD11b Antibody (clone M1/70, IHC, IF) LS‑C357743
Antibody:
ITGAM / CD11b Rat anti-Mouse Monoclonal (M1/70) Antibody
Application:
IHC, IHC-Fr, IF, IP, Flo, ELISA, Block, Func
Reactivity:
Mouse, Human, Chimpanzee, Baboon, Rabbit, Cynomolgus, Rhesus monkey
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ITGAM / CD11b Rat anti-Mouse Monoclonal (M1/70) Antibody
Application:
IHC, IHC-Fr, IF, IP, Flo, ELISA, Block, Func
Reactivity:
Mouse, Human, Chimpanzee, Baboon, Rabbit, Cynomolgus, Rhesus monkey
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
CD11b antibody LS-C357743 is an unconjugated rat monoclonal antibody to CD11b (ITGAM) from mouse. It is reactive with human, mouse, baboon and other species. Validated for Block, ELISA, Flow, Func, IF, IHC and IP.
Target
Mouse ITGAM / CD11b
Synonyms
ITGAM | Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain
Host
Rat
Reactivity
Mouse, Human, Chimpanzee, Baboon, Rabbit, Cynomolgus, Rhesus monkey
(tested or 100% immunogen sequence identity)
Clonality
IgG2b,k
Monoclonal
Clone
M1/70
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified.
Also available Azide-free, BSA-free.
Immunogen
B10 mouse spleen cells enriched for T lymphocytes.
Specificity
Mouse ITGAM / CD11b
Applications
- IHC
- IHC - Frozen (0.5 - 1 µg/ml)
- Immunofluorescence (0.5 - 1 µg/ml)
- Immunoprecipitation
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
- ELISA
- Blocking
- Functional Assay
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. ELISA: Order BSA-free antibody format for coating.
Presentation
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ITGAM / CD11b
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Featured Products
Species:
Mouse, Human, Rabbit
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Immunofluorescence, Immunoprecipitation, Flow Cytometry
Species:
Mouse, Human, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Dog, Bovine, Cat, Goat, Pig, Mustelid
Applications:
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/28/2024
Date Requested: 11/28/2024
