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| Catalog Number | Size | Price |
|---|---|---|
| LS-C391450-7 | 7 ml | $574 |
Monoclonal Mouse anti‑Human Pan Cytokeratin Antibody (clone PAN‑CK (Cocktail), Ready‑to‑Use, IHC, IF, WB) LS‑C391450
Monoclonal Mouse anti‑Human Pan Cytokeratin Antibody (clone PAN‑CK (Cocktail), Ready‑to‑Use, IHC, IF, WB) LS‑C391450
Antibody:
Pan Cytokeratin Mouse anti-Human Monoclonal (Ready-to-Use) (PAN-CK (Cocktail)) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Chicken
Format:
Unconjugated, Ready-to-Use
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
Pan Cytokeratin Mouse anti-Human Monoclonal (Ready-to-Use) (PAN-CK (Cocktail)) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Chicken
Format:
Unconjugated, Ready-to-Use
Other formats:
Specifications
Description
Pan Cytokeratin antibody LS-C391450 is an unconjugated mouse monoclonal antibody to Pan Cytokeratin from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF, IHC and WB.
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Chicken
(tested or 100% immunogen sequence identity)
Clonality
IgG,k
Monoclonal
Clone
PAN-CK (Cocktail)
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Ready-to-Use.
Also available Unmodified or Azide-free, BSA-free.
Immunogen
Human epidermal keratin
Specificity
Human Pan Cytokeratin
Applications
- IHC
- IHC - Paraffin (1:1)
- Immunofluorescence
- Western blot
- Flow Cytometry
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1). 64kDa (CK3). 59kDa (CK4). 58kDa (CK5). 56kDa (CK6). 55kDa (CK7). 52kDa (CK8). 56.5kDa (CK10). 53kDa (CK13). 50kDa (CK14). 50kDa (CK15). 48kDa (CK16). 46kDa (CK17). 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas. Optimal dilution of the pan Cytokeratin antibody cocktail should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
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Featured Products
Species:
Human, Mammal
Applications:
IHC - Paraffin, ICC, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Mammal
Applications:
IHC - Paraffin, ICC, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Species:
Human, Mammal
Applications:
IHC - Paraffin, ICC, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
