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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4901-50 | 50 µl (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human ACTG2 Antibody (aa1‑50, IHC, WB) LS‑B4901
PathPlus™ Polyclonal Rabbit anti‑Human ACTG2 Antibody (aa1‑50, IHC, WB) LS‑B4901
Note: This antibody replaces LS-C118385
Antibody:
ACTG2 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ACTG2 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
Smooth muscle gamma actin (ACTG2) is a protein that is a component of the cytoskeleton in smooth muscle and is involved in cell motility. Mutations of the ACTG2 gene result in visceral myopathy, a rare form of myopathic pseudo-obstruction. ACTG2 is localized to the cytoplasm of myoepithelial cells, predominantly in enteric tissues. Aberrant expression has been reported in several types of cancer such as colorectal, breast, laryngeal, and small intestinal neuroendocrine tumors, which may affect chemotherapy sensitivity. Staining is used to identify smooth muscle cells in normal tissue and in disease.
References:
Mol Cell Biol. 1991;11(6):3296-3306. PMID: 1710027; PLoS Genet. 2014;10(3):e1004258. doi: 10.1371/journal.pgen.1004258; BMC Endocr Disord. 2016;16:19. doi: 10.1186/s12902-016-0100-3; Cancer Biother Radiopharm. 2013;28(7): 552-558. doi: 10.1089/cbr.2012.1431; Acta Oncol. 2007;46(5):651-658. doi: 10.1080/02841860601156157; Int J Clin Exp Pathol. 2013;6(7):1351-1361. PMID: 23826416
Target
Human ACTG2
Synonyms
ACTG2 | ACTA3 | Actin-like protein | ACTSG | ACTE | Actin, alpha cardiac | ACTL3 | Alpha-actin 3 | Alpha-actin-3 | Smooth muscle gamma-actin | Gamma-2-actin | Smooth muscle gamma actin
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human Actin-gamma2. (AA Range: 1-50)
Epitope
aa1-50
Specificity
Actin-gamma2 Antibody detects endogenous levels of total Actin-gamma2 protein.
Applications
- IHC
- IHC - Paraffin (1:200)
- Western blot (1:500 - 1:1000)
- Peptide Enzyme-Linked Immunosorbent Assay (1:20000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot: Predicted MW 41 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ACTG2
Validation
Anti-ACTG2 / Gamma-2 Actin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-ACTG2 / Gamma-2 Actin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-ACTG2 / Gamma-2 Actin antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-ACTG2 / Gamma-2 Actin antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
See More About...
LSBio Ratings
PathPlus™ ACTG2 Antibody (aa1-50) for IHC, WB/Western LS-B4901 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat, Bovine, Rabbit, Chicken
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/22/2024
Date Requested: 12/22/2024
