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| Catalog Number | Size | Price |
|---|---|---|
| LS-A2034-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human ADGRD1 / GPR133 Antibody (N‑Terminus, IHC) LS‑A2034
PathPlus™ Polyclonal Rabbit anti‑Human ADGRD1 / GPR133 Antibody (N‑Terminus, IHC) LS‑A2034
Note: This antibody replaces LS-C66977
Antibody:
ADGRD1 / GPR133 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
ADGRD1 / GPR133 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
ADGRD1 is an orphan adhesion G protein-coupled receptor that is transcriptionally upregulated by hypoxia in a Hif1a dependent manner. It is a critical regulator of the response to hypoxia and tumor growth in glioblastoma, and its expression levels are inversely correlated with patient survival. The receptor is widely expressed in human tissues.
References: Oncogenesis. 2016 Oct; 5(10): e263.
Target
Human ADGRD1 / GPR133
Synonyms
ADGRD1 | G protein-coupled receptor 133 | GPR133 | PGR25
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from N-Terminus extracellular domain of human GPR133. Percent identity with other species by BLAST analysis: Human, Monkey (100%); Gorilla, Gibbon (95%); Marmoset (90%).
Epitope
N-Terminus
Specificity
Human GPR133. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ENTPD4 (50%).
Applications
- IHC
- IHC - Paraffin (10 - 20 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADGRD1 / GPR133
Validation
Brain, Glioblastoma
Brain, Glioblastoma
Lung, non small cell carcinoma
Lung, non small cell carcinoma
Brain, Glioblastoma
Brain, Glioblastoma
Anti-GPR133 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR133 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR133 antibody IHC of human ovary, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR133 antibody IHC of human ovary, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ ADGRD1 / GPR133 Antibody (N-Terminus) for IHC LS-A2034 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Dog, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Dog, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/28/2024
Date Requested: 11/28/2024
