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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16581-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human BAD Antibody (IHC, WB) LS‑B16581
PathPlus™ Polyclonal Rabbit anti‑Human BAD Antibody (IHC, WB) LS‑B16581
Note: This antibody replaces LS-C776305
Antibody:
BAD Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P, WB
Reactivity:
Human, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
BAD Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P, WB
Reactivity:
Human, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
BAD (Bcl-2-associated agonist of cell death) is a member of the BCL-2 family of proteins and functions to promote cell death. BAD regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL, thereby preventing them from binding with Bax. BAD activity is regulated by its phosphorylation; it is inactivated by kinases such as Akt and MAP, promoting cell survival, whereas JNK-induced phosphorylation promotes the apoptotic role of Bad.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human BAD
Synonyms
BAD | BBC2 | Bcl-2-like protein 8 | BCL2-binding component 6 | BCL2L8 | BBC6 | BCL-X/BCL-2 binding protein | Bcl-2-binding component 6 | Bcl2 antagonist of cell death | BCL2-binding protein | Bcl2-L-8
Host
Rabbit
Reactivity
Human, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Peptide Affinity Purified
Modifications
Unmodified
Immunogen
Synthetic peptide from the mid-protein of Human BAD (aa. 60-90)
Specificity
Detects 28 kDa. Band is higher than the predicted molecular weight due to post translational modifications.
Applications
- IHC - Paraffin (5 µg/ml)
- Western blot (1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Applications should be user optimized.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide, 50% Glycerol
Storage
Store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BAD
Validation
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ BAD Antibody for IHC, WB/Western LS-B16581 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Mouse, Monkey, Rat, Bovine, Dog, Hamster, Pig, Rabbit, Sheep, Drosophila
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Mouse, Human, Monkey, Rat
Applications:
Western blot, Immunoprecipitation, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
