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| Catalog Number | Size | Price |
|---|---|---|
| LS-A7980-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human CDC7 Antibody (Kinase Domain, IHC) LS‑A7980
PathPlus™ Polyclonal Rabbit anti‑Human CDC7 Antibody (Kinase Domain, IHC) LS‑A7980
Note: This antibody replaces LS-C78940
Antibody:
CDC7 Rabbit anti-Human Polyclonal (Kinase Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Bat, Bovine, Dog, Horse, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
CDC7 Rabbit anti-Human Polyclonal (Kinase Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Bat, Bovine, Dog, Horse, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
Cell division cycle 7 (CDC7) is a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of CDC7 product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human CDC7
Synonyms
CDC7 | Cdc7 Kinase | CDC7-like 1 | CDC7L1 | HsCDC7 | HuCDC7 | CDC7-related kinase | Hsk1 | MuCdc7
Host
Rabbit
Reactivity
Human, Bat, Bovine, Dog, Horse, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Rat, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from kinase domain of human CDC7. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Opossum (100%); Monkey, Mouse, Rat, Hamster, Platypus (95%); Turkey, Chicken, Lizard, Xenopus (89%); Stickleback, Pufferfish, Zebrafish (84%).
Epitope
Kinase Domain
Specificity
Human CDC7. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (6.5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CDC7
Validation
Brain, Alzheimer's neurofibrillary tangle
Brain, Alzheimer's neurofibrillary tangle
Lymph node, Hodgkin's Disease
Lymph node, Hodgkin's Disease
Anti-CDC7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CDC7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CDC7 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CDC7 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CDC7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CDC7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ CDC7 Antibody (Kinase Domain) for IHC LS-A7980 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Requested From: United States
Date Requested: 12/23/2024
Date Requested: 12/23/2024
