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| Catalog Number | Size | Price |
|---|---|---|
| LS-A2736-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human CELSR3 Antibody (N‑Terminus, IHC) LS‑A2736
PathPlus™ Polyclonal Rabbit anti‑Human CELSR3 Antibody (N‑Terminus, IHC) LS‑A2736
Antibody:
CELSR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
CELSR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
Cadherin, EGF LAG seven-pass G-type receptor 3 (CELSR3) belongs to the flamingo subfamily of proteins, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. CELSR3 is a plasma membrane protein containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. It is functionally involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human CELSR3
Synonyms
CELSR3 | Anchor protein | Cadherin family member 11 | CDHF11 | EGF-like protein 1 | EGF-like-domain, multiple 1 | Epidermal growth factor-like 1 | Flamingo homolog 1 | FMI1 | KIAA0812 | MEGF2 | Megf3 | HFMI1 | Multiple EGF-like domains 2 | RESDA1 | EGFL1
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 15 amino acid peptide from N-Terminus extracellular domain of human CELSR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Horse, Rabbit (100%); Opossum (93%).
Epitope
N-Terminus
Specificity
Human CELSR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (4 - 11 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CELSR3
Validation
Brain, Glioblastoma
Brain, Glioblastoma
Brain, Alzheimer's, amyloid cores within senile plaques
Brain, Alzheimer's, amyloid cores within senile plaques
Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia
Anti-CELSR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CELSR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CELSR3 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CELSR3 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CELSR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CELSR3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CELSR3 antibody IHC of human brain, Purkinje cell layer. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CELSR3 antibody IHC of human brain, Purkinje cell layer. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ CELSR3 Antibody (N-Terminus) for IHC LS-A2736 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Bovine
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/23/2024
Date Requested: 12/23/2024
