Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B16145-100 100 µl (1 mg/ml) $460 
CLDN18 / Claudin 18 Antibody - Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
CLDN18 / Claudin 18 Antibody - Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
CLDN18 / Claudin 18 Antibody - Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
CLDN18 / Claudin 18 Antibody - Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
1 of 2
2 of 2

PathPlus™ Monoclonal Mouse anti‑Human CLDN18 / Claudin 18 Antibody (IHC) LS‑B16145

PathPlus™ Monoclonal Mouse anti‑Human CLDN18 / Claudin 18 Antibody (IHC) LS‑B16145

Note: This antibody replaces LS-C744501
Antibody:
CLDN18 / Claudin 18 Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B16145-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
CLDN18 / Claudin 18 Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
CLDN18/claudin 18 is a member of the claudin family of integral membrane proteins that comprise tight junction strands. These are formed at points of cell-cell adhesion at the plasma membrane in epithelial cells. There are two splice variants, one expressed in the gastric mucosa and the other in lung. The gastric isoform is expressed in gastric tumors as well as tumors of other tissues, including the lung, ovary, pancreas, and esophagus. Staining is used to identify gastrointestinal and pancreatobiliary neoplasms such as gastrointestinal signet ring cell carcinoma, pancreatic ductal adenocarcinomas, and intrahepatic cholangiocarcinoma. References: Mol Cell Biol. 2001;21(21):7380-7390. doi: 10.1128/MCB.21.21.7380-7390.2001; Clin Cancer Res. 2008;14(23):7624-7634. doi: 10.1158/1078-0432.CCR-08-1547; Gene. 2011;481(2):83-92. doi: 10.1016/j.gene.2011.04.007; Am J Surg Pathol. 2008;32(8):1182-1189. doi: 10.1097/PAS.0b013e318163a8f8; J Histochem Cytochem. 2011;59(10):942-952. doi: 10.1369/0022155411420569; Virchows Arch. 2011;459(1):73-80. doi: 10.1007/s00428-011-1092-z.
Target
Human CLDN18 / Claudin 18
Synonyms
CLDN18 | Claudin 18 | Claudin-18 | SFTPJ | SFTA5 | Surfactant associated 5
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Conjugations
Unconjugated
Purification
Immunogen affinity purified
Modifications
Unmodified
Immunogen
Synthetic Claudin 18
Applications
  • IHC (1:200 - 1:400)
  • IHC - Paraffin (1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Use Heat-induced epitope retrieval (HIER) Citrate buffer of pH 6.0 Recommended IHC controls tissues are Stomach. Resulting localization is Membranous
Presentation
PBS, pH7.4, 50% glycerol, 0.03% Proclin300
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CLDN18 / Claudin 18
P56856 NM_016369 NP_057453.1

Validation

CLDN18 / Claudin 18 Antibody - Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)

CLDN18 / Claudin 18 Antibody - Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ CLDN18 / Claudin 18 Antibody for IHC LS-B16145 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 7/20/2024