Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-B16088-100 | 100 µl (1 mg/ml) | $460 |
1 of 3
2 of 3
3 of 3
PathPlus™ Polyclonal Rabbit anti‑Human CNN1 / Calponin Antibody (Internal, IHC, WB) LS‑B16088
PathPlus™ Polyclonal Rabbit anti‑Human CNN1 / Calponin Antibody (Internal, IHC, WB) LS‑B16088
Note: This antibody replaces LS-C354304
Antibody:
CNN1 / Calponin Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CNN1 / Calponin Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
Calponin (CNN1) is a smooth muscle protein with functional roles in proliferation, angiogenesis and migration (O’Kelly, 2008). It is a negative regulator of smooth muscle contraction via its inhibition of actomyosin interaction. As a marker, calponin is used to identify myoepithelial cells. It stains positively in the cytoplasm around the nucleus in myoepithelial cells, stromal myofibroblasts, and vascular smooth muscle.
References: Intl J Onc. 2008 Jul; 33.1; 59-67, PMID: 18575751; Clin Onc. 2014 Aug; 5.3; 382-392, PMID: 25114853; Trends Biochem Sci. 1994 Sep;19(9):362-8, PMID: 7985229
Target
Human CNN1 / Calponin
Synonyms
CNN1 | Basic calponin | Calponin | Calponin-1 | Calponins, basic | Calponin H1, smooth muscle | SMCC | Sm-Calp
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human Calponin 1.
Epitope
Internal
Specificity
Recognizes endogenous levels of Calponin 1 protein.
Applications
- IHC - Paraffin (1:100)
- Western blot (1:500 - 1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CNN1 / Calponin
Validation
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ CNN1 / Calponin Antibody (Internal) for IHC, WB/Western LS-B16088 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Turkey, Human, Mouse, Rat, Chicken
Applications:
IHC, IHC - Paraffin, ICC, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Reactivity:
Mouse
Range:
0.313-20 ng/ml
Reactivity:
Human
Range:
0.312-20 ng/ml
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
