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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16452-50 | 50 µg (0.5 mg/ml) | $460 |
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PathPlus™ Polyclonal Goat anti‑Human EFNB2 / Ephrin B2 Antibody (aa62‑74, IHC, WB) LS‑B16452
PathPlus™ Polyclonal Goat anti‑Human EFNB2 / Ephrin B2 Antibody (aa62‑74, IHC, WB) LS‑B16452
Note: This antibody replaces LS-C139620
Antibody:
EFNB2 / Ephrin B2 Goat anti-Human Polyclonal (aa62-74) Antibody
Application:
IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
EFNB2 / Ephrin B2 Goat anti-Human Polyclonal (aa62-74) Antibody
Application:
IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken
Format:
Unconjugated, Unmodified
Specifications
Description
EFNB2 (ephrin B2) is a member of the ephrin family, receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNB2 binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4, it plays a central role in cardiac morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. It also plays a role in the orientation of longitudinally projecting axons.
References: Journal of Cell Science 2010 123: 1235-1246; Cell Communication and Signalingvolume 17, Article number: 29 (2019)
Target
Human EFNB2 / Ephrin B2
Synonyms
EFNB2 | Ephrin-B2 | EPLG5 | Ephrin B2 | HTK ligand | Htk-L | LERK-5 | LERK5 | Ligand of eph-related kinase 5 | HTKL
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
Peptide with sequence CPKVDSKTVGQYE, from the internal region of the protein sequence according to NP_004084.1.
Epitope
aa62-74
Specificity
Human EFNB2 / Ephrin B2.
Applications
- IHC - Paraffin (3.75 µg/ml)
- Western blot (0.1 - 0.3 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:16000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 35kD band observed in Human, Mouse and Rat Lung lysates (calculated MW of 36.9kD according to NP_004084.1). Recommended concentration: 0.1-0.3 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About EFNB2 / Ephrin B2
Validation
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ EFNB2 / Ephrin B2 Antibody (aa62-74) for IHC, WB/Western LS-B16452 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
