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| Catalog Number | Size | Price |
|---|---|---|
| LS-A2091-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human FKSG80 / GPR81 Antibody (Extracellular Domain, IHC) LS‑A2091
PathPlus™ Polyclonal Rabbit anti‑Human FKSG80 / GPR81 Antibody (Extracellular Domain, IHC) LS‑A2091
Antibody:
FKSG80 / GPR81 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Rat, Bat, Dog, Hamster, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
FKSG80 / GPR81 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Rat, Bat, Dog, Hamster, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
Hydroxycarboxylic acid receptor 1 (HCAR1) acts as a receptor for L-lactate / lactic acid and mediates its anti-lipolytic effect in fat cells through a G(i)-protein-mediated pathway. In immunohistochemistry, HCAR1 has highest membranous positivity in the parathyroid gland, and has moderate expression in the breast, the ductus deferens, the salivary gland, adipose tissue, the spleen, blood and is present at low levels in the spinal cord and a few other tissues throughout the body.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human FKSG80 / GPR81
Synonyms
HCAR1 | FKSG80 | G protein-coupled receptor 81 | G-protein coupled receptor 104 | G protein-coupled receptor 104 | G-protein coupled receptor 81 | GPR81 | GPR104 | LACR1 | HCA1 | TA-GPCR | Lactate receptor 1
Host
Rabbit
Reactivity
Human, Monkey, Rat, Bat, Dog, Hamster, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Horse, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 2nd extracellular domain of human GPR81. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Rat, Dog, Bat, Hamster, Panda, Rabbit, Opossum (100%); Mouse, Horse, Pig, Platypus (94%); Bovine (88%); Elephant (81%).
Epitope
Extracellular Domain
Specificity
Human GPR81. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (3 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About FKSG80 / GPR81
Validation
Brain, Alzheimer's, neurons and senile plaque
Brain, Alzheimer's, neurons and senile plaque
Anti-FKSG80 / GPR81 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FKSG80 / GPR81 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Brain, Cerebellum, Purkinje Cell Layer
Brain, Cerebellum, Purkinje Cell Layer
Brain, Glioblastoma
Brain, Glioblastoma
Anti-FKSG80 / GPR81 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FKSG80 / GPR81 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FKSG80 / GPR81 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FKSG80 / GPR81 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR81 antibody IHC of human pituitary, anterior. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR81 antibody IHC of human pituitary, anterior. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FKSG80 / GPR81 antibody IHC of human pancreas islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FKSG80 / GPR81 antibody IHC of human pancreas islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ FKSG80 / GPR81 Antibody (Extracellular Domain) for IHC LS-A2091 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/21/2024
Date Requested: 11/21/2024
