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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16183-0.05 | 0.05 ml | $460 |
PathPlus™ Monoclonal Mouse anti‑Human Hepatocyte Specific Antigen Antibody (clone OCH1E5, IHC) LS‑B16183
PathPlus™ Monoclonal Mouse anti‑Human Hepatocyte Specific Antigen Antibody (clone OCH1E5, IHC) LS‑B16183
Note: This antibody replaces LS-C312061
Antibody:
Hepatocyte Specific Antigen Mouse anti-Human Monoclonal (OCH1E5) Antibody
Application:
IHC-P, IHC-Fr
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
Hepatocyte Specific Antigen Mouse anti-Human Monoclonal (OCH1E5) Antibody
Application:
IHC-P, IHC-Fr
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
Hepatocyte Specific Antigen (HepPar1, Hep paraffin 1, OCH1E5) is an antigen expressed in hepatocyte mitochondria. In immunohistochemistry, it is considered a sensitive marker for differentiating hepatocellular carcinomas (HCC) from other cancers such as cholangiocarcinomas. It may also be a useful biomarker for characterizing metaplasia in the intestine and early Barrett esophagus. Hepatocyte Specific Antigen is also found in some gastric adenocarcinomas as well as in a few other non-hepatic tumors. In normal tissue, it has granular cytoplasmic positivity in hepatocytes and small intestine epithelium.
References: Mod Pathol. 2003 Feb;16(2):137-44, PMID: 12591966; Am J Clin Pathol 2012;137:111, PMID: 22180484; Malays J Pathol 2006;28:87, PMID: 18376797
Target
Human Hepatocyte Specific Antigen
Synonyms
HepPar1 | Hep Par | Hepatocyte Paraffin 1 | OCH1E5
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Clone
OCH1E5
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified.
Also available Ready-to-Use.
Applications
- IHC - Paraffin (1:50)
- IHC - Frozen (1:100 - 1:500)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: Paraffin and frozen. Control tissue: Liver. Localization: Cytoplasmic.
Presentation
Filter sterilized and diluted in buffer, pH 7.5, BSA, Sodium Azide
Storage
Store at 2-8°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Validation
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ Hepatocyte Specific Antigen Antibody (clone OCH1E5) for IHC LS-B16183 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Dog
Applications:
IHC, IHC - Paraffin
Species:
Human, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence
Species:
Human, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence
Species:
Human, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence
Species:
Human, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence
Species:
Human, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/3/2024
Date Requested: 11/3/2024
