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| Catalog Number | Size | Price |
|---|---|---|
| LS-B8116-100 | 100 µl | $440 |
PathPlus™ Monoclonal Mouse anti‑Human KRT10 / CK10 / Cytokeratin 10 Antibody (clone DE‑K10, Concentrated, IHC, WB) LS‑B8116
PathPlus™ Monoclonal Mouse anti‑Human KRT10 / CK10 / Cytokeratin 10 Antibody (clone DE‑K10, Concentrated, IHC, WB) LS‑B8116
Note: This antibody replaces LS-C153040
Antibody:
KRT10 / CK10 / Cytokeratin 10 Mouse anti-Human Monoclonal (Concentrated) (DE-K10) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Concentrated
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
KRT10 / CK10 / Cytokeratin 10 Mouse anti-Human Monoclonal (Concentrated) (DE-K10) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Concentrated
Specifications
Description
KRT10 (Cytokeratin 10, CK10) is the main type I keratin expressed in the post-mitotic keratinizing cells of the skin and other cornifying stratified epithelia. KRT10 is a negative regulator of cell division, and forms heterodimers with KRT1 or KRT2. KRT10 is associated with cyclic ichthyosis and epidermolytic hyperkeratosis.
References: J Anat 2009 214(4):516; Arch Biochem Biophys 2011 508(2):123
Target
Human KRT10 / CK10 / Cytokeratin 10
Synonyms
KRT10 | BIE | BCIE | CK10 | Cytokeratin 10 | Cytokeratin-10 | EHK | Keratin-10 | KPP | Keratin 10 | CK-10 | K10
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
DE-K10
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Concentrated
Immunogen
Antigen derived from cytoskeletal preparation from human epidermis
Specificity
Reacts in immunoblots with the 56.6 kD cytokeratin protein. Specifically recognizes cytokeratin 10. Positive control: Squamous cell carcinoma.
Applications
- IHC
- IHC - Paraffin (1:100)
- IHC - Frozen (1:5 - 1:10)
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
For immunohistochemistry on frozen sections fixation with acetone for 5 min. at -20?C is recommended. For use in paraffin sections fixation with neutral formalin and a pretreatment with pronase or trypsin is also recommended. Dilution buffer: 0.15 M PBS with 1% BSA and 0.1% sodium azide.
Presentation
0.15 M PBS, 0.02% Sodium Azide, 1% BSA
Storage
Store at 2-8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About KRT10 / CK10 / Cytokeratin 10
Validation
Anti-Keratin 10 / Cytokeratin 10 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-Keratin 10 / Cytokeratin 10 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
See More About...
LSBio Ratings
PathPlus™ KRT10 / CK10 / Cytokeratin 10 Antibody (clone DE-K10, Concentrated) for IHC, WB/Western LS-B8116 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Species:
Human, Cat, Dog
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC - Paraffin
Species:
Human
Applications:
IHC - Paraffin
Species:
Human
Applications:
IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat, Dog, Pig
Applications:
IHC, IHC - Frozen, ICC, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
