Galectin 3 (LGALS3) is a protein that binds glycans and is involved in cell-cell and cell-matrix interactions, growth and proliferation, differentiation and inflammation. It plays a role in various cell functions, including apoptosis, immunity, angiogenesis, macrophage activation, cell adhesion, and T-cell regulation. It is expressed in the cytoplasm, the nucleus, on the cell surface and the extracellular space. It is expressed in a wide variety of cell types including fibroblasts, epithelial cells in many organs, and immune cells. References: Sciacchitano 2018 Int J Mol Sci 19(2):379; Ahmad 2004 Glycobiology 14(9):817