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| Catalog Number | Size | Price |
|---|---|---|
| LS-A426-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human LPAR5 / GPR92 Antibody (Cytoplasmic Domain, IHC) LS‑A426
PathPlus™ Polyclonal Rabbit anti‑Human LPAR5 / GPR92 Antibody (Cytoplasmic Domain, IHC) LS‑A426
Note: This antibody replaces LS-C66972
Antibody:
LPAR5 / GPR92 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Overview
Antibody:
LPAR5 / GPR92 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
Lysophosphatidic acid receptor 5 (LPAR5) is a member of the rhodopsin class of G protein-coupled transmembrane receptors. LPAR5 transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human LPAR5 / GPR92
Synonyms
LPAR5 | G-protein coupled receptor 92 | GPR92 | GPR93 | LPA receptor 5 | LPA-5 | KPG_010 | LPA5 | G protein-coupled receptor 92 | G-protein coupled receptor 93
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Bat, Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human LPAR5 / GPR92. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Panda (100%); Marmoset, Elephant, Bat, Bovine (95%); Rat, Dog, Rabbit, Pig, Opossum (89%); Monkey (84%).
Epitope
Cytoplasmic Domain
Specificity
Human LPAR5 / GPR92. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (1 - 5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About LPAR5 / GPR92
Validation
Brain, glioblastoma
Brain, glioblastoma
Anti-LPAR5 / GPR92 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-LPAR5 / GPR92 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Brain, Cortex, Neuron
Brain, Cortex, Neuron
Brain, Alzheimer's disease senile plaque
Brain, Alzheimer's disease senile plaque
See More About...
LSBio Ratings
PathPlus™ LPAR5 / GPR92 Antibody (Cytoplasmic Domain) for IHC LS-A426 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
LPA5 is abundantly expressed by human mast cells and important for lysophosphatidic acid induced MIP-1 release. Lundequist A, Boyce JA. PloS one. 2011 6:e18192. (Flo; Human)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin, ICC
Species:
Human
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
