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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4814-125 | 125 µl | $460 |
1 of 2
2 of 2
PathPlus™ Monoclonal Rat anti‑Bovine MBP / Myelin Basic Protein Antibody (clone 12, aa82‑87, IHC, WB) LS‑B4814
PathPlus™ Monoclonal Rat anti‑Bovine MBP / Myelin Basic Protein Antibody (clone 12, aa82‑87, IHC, WB) LS‑B4814
Note: This antibody replaces LS-C45094
Antibody:
MBP / Myelin Basic Protein Rat anti-Bovine Monoclonal (aa82-87) (12) Antibody
Application:
IHC, IHC-P, WB, ELISA, RIA
Reactivity:
Bovine, Human, Mouse, Rat, Guinea pig, Pig, Rabbit, Sheep, Chicken, Mammal
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
MBP / Myelin Basic Protein Rat anti-Bovine Monoclonal (aa82-87) (12) Antibody
Application:
IHC, IHC-P, WB, ELISA, RIA
Reactivity:
Bovine, Human, Mouse, Rat, Guinea pig, Pig, Rabbit, Sheep, Chicken, Mammal
Format:
Unconjugated, Unmodified
Specifications
Description
Myelin Basic Protein (MBP) is the second most abundant protein of the myelin membrane sheath in the central nervous system. It is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin. MBP has roles in myelin formation and stabilization, remyelination and brain development, and may be involved in signaling. MBP has a role in diseases of demyelination such as multiple sclerosis. It is expressed in oligodendrocytes and Schwann cells of the central nervous system.
References: Cell mol Life Sci 2006 63(17):1945
Target
Bovine MBP / Myelin Basic Protein
Synonyms
MBP | Myelin A1 protein | Myelin basic protein
Host
Rat
Reactivity
Bovine, Human, Mouse, Rat, Guinea pig, Pig, Rabbit, Sheep, Chicken, Mammal
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Clone
12
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Bovine MBP (AA 82-87)
Epitope
aa82-87
Specificity
Reacts with myelin basic protein from a wide range of species. The Reacts weakly with peptides ending in the Phe 91 where the 91-92 Phe-Phe bond is broken. Synthetic peptide Reacts very well, as does intact MBP. Further epitope analysis indicates binding to a region defined by amino acids 82-87 (DENPVV). Clone 12 has been reported as being suitable for use in Western blotting.
Applications
- IHC
- IHC - Paraffin (1:50)
- Western blot
- ELISA
- Radioimmunoassay
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Failed Applications
- IHC - Frozen
Presentation
Tissue culture supernatant, 0.1M Tris, 0.1% sodium azide
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MBP / Myelin Basic Protein
Validation
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-Myelin Basic Protein antibody IHC of human myelin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-Myelin Basic Protein antibody IHC of human myelin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
See More About...
LSBio Ratings
PathPlus™ MBP / Myelin Basic Protein Antibody (aa82-87, clone 12) for IHC, WB/Western, ELISA LS-B4814 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, ICC, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC - Paraffin, ICC, Western blot, Flow Cytometry, ELISA
Species:
Human, Mouse, Rat, Goat, Rabbit, Sheep, Primate
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Species:
Rat
Applications:
IHC, IHC - Paraffin, ICC, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
