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Catalog Number Size Price
LS-B13706-50 50 µl (1 mg/ml) $460 
NGF Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
NGF Antibody - Western blot analysis of pro-NGF beta expression in Jurkat (A); NIH3T3 (B) whole cell lysates.
NGF Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
NGF Antibody - Western blot analysis of pro-NGF beta expression in Jurkat (A); NIH3T3 (B) whole cell lysates.
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PathPlus™ Polyclonal Rabbit anti‑Human NGF Antibody (Internal, IHC, WB) LS‑B13706

PathPlus™ Polyclonal Rabbit anti‑Human NGF Antibody (Internal, IHC, WB) LS‑B13706

Note: This antibody replaces LS-C356223
Antibody:
NGF Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B13706-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
NGF Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
NGF (Nerve growth factor) is a neurotrophic protein with important functions in maintaining the integrity and proper function of target neurons in the developing and adult brain. It controls the plasticity, differentiation and proliferation of cholinergic neurons in the nervous system, which are important for cognition. NGF metabolism is altered in Alzheimer’s disease, which leads to neuronal atrophy and a loss of cortical synapses. Several decades of study indicates that NGF has neuro-protective and regenerative characteristics in neurodegenerative diseases such as Alzheimer’s and in aging. Delivery of NGF to cholinergic cell bodies in the cortex and hippocampus has been attempted as a means of rehabilitating cholinergic signaling and suppressing cognitive decline. Separately, high NGF levels in the plasma are correlated with recent feelings of romantic love, in part due to its stimulation of adrenocorticotrophic hormone and cortisol release. In immunohistochemistry, NGF has variable levels of secretory, extracellular and cytoplasmic positivity in most tissues throughout the body. References: Front Neurosci. 2019 Feb 5;13:38, PMID: 30804738; Rev Neurosci. 1994 Jul-Sep;5(3):179-211, PMID: 7889213; Progress in Brain Research. 2004. 146: 111–26,PMID: 14699960; Brain Research. 217 (1): 207–211, PMID: 6114784;
Target
Human NGF
Synonyms
NGF | Beta-nerve growth factor | ProNGF | Beta-NGF | HSAN5 | NGFB
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human pro-NGF beta.
Epitope
Internal
Specificity
Recognizes endogenous levels of pro-NGF beta protein.
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About NGF
P01138 NM_002506 NP_002497.2

Validation

NGF Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ NGF Antibody (Internal) for IHC, WB/Western LS-B13706 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/24/2024