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| Catalog Number | Size | Price |
|---|---|---|
| LS-A825-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human NMBR Antibody (Cytoplasmic Domain, IHC) LS‑A825
PathPlus™ Polyclonal Rabbit anti‑Human NMBR Antibody (Cytoplasmic Domain, IHC) LS‑A825
Antibody:
NMBR Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Mouse, Bat, Bovine, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
NMBR Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Mouse, Bat, Bovine, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
Neuromedin B receptor (NMBR) a Bombesin Receptor that activates phospholipase and protein kinase C and enhances calcium mobilization. NMBR binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human NMBR
Synonyms
NMBR | Bombesin BB1 receptor | Neuromedin-B receptor | Neuromedin B receptor | NMB-preferring receptor | NMB-R
Host
Rabbit
Reactivity
Human, Mouse, Bat, Bovine, Horse, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Rat, Dog, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human NMBR. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Panda, Bovine, Bat, Horse, Rabbit, Pig (100%); Marmoset, Rat, Hamster, Dog, Opossum (94%); Platypus (88%); Elephant, Xenopus (81%).
Epitope
Cytoplasmic Domain
Specificity
Human NMBR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (5 - 10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NMBR
Validation
Anti-NMBR antibody IHC of human brain, glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NMBR antibody IHC of human brain, glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NMBR antibody IHC of human brain, olfactory bulb. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NMBR antibody IHC of human brain, olfactory bulb. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NMBR antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NMBR antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NMBR antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
Anti-NMBR antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
Anti-NMBR antibody IHC of human lung, carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
Anti-NMBR antibody IHC of human lung, carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 16 ug/ml.
See More About...
LSBio Ratings
PathPlus™ NMBR Antibody (Cytoplasmic Domain) for IHC LS-A825 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Mechanism of bombesin-induced tonic contraction of the porcine lower esophageal sphincter. Ching-Chung Tsai, Li-Ching Chang, Kai-Jen Lin, Shu-Leei Tey, Yu-Tsun Su, Ching-Wen Liu, Tong-Rong Tsai, Shih-Che Huang. Scientific reports. 2015 November;5:15879.
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
