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| Catalog Number | Size | Price |
|---|---|---|
| LS-A9584-50 | 50 µg (1 mg/ml) | $440 |
1 of 2
2 of 2
PathPlus™ Polyclonal Rabbit anti‑Human P2RX3 / P2X3 Antibody (C‑Terminus, IHC) LS‑A9584
PathPlus™ Polyclonal Rabbit anti‑Human P2RX3 / P2X3 Antibody (C‑Terminus, IHC) LS‑A9584
Antibody:
P2RX3 / P2X3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
P2RX3 / P2X3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
P2RX3 / P2X3 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human P2RX3 / P2X3
Synonyms
P2RX3 | ATP receptor | p2X3 | p2X3 purinoceptor | p2X purinoceptor 3 | Purinergic receptor P2X3 | Purinoceptor P2X3 | Purinergic receptor | p2RX3 | p2X receptor 3 | p2X receptor, subunit 3
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Predicted
Bat, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 15 amino acid peptide from C-Terminus cytoplasmic domain of human P2RX3 / P2X3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Bat, Rabbit, Opossum (93%); Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse (87%).
Epitope
C-Terminus
Specificity
Human P2RX3 / P2X3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Antigen retrieval requires Proteinase K treatment.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About P2RX3 / P2X3
Validation
Anti-P2RX3 / P2X3 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RX3 / P2X3 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RX3 / P2X3 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RX3 / P2X3 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ P2RX3 / P2X3 Antibody (C-Terminus) for IHC LS-A9584 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Rat, Mouse, Hamster
Applications:
IHC, ICC, Immunofluorescence, Western blot
Species:
Human, Mouse, Rat
Applications:
Western blot, ELISA
Source:
Human
Tag:
Myc-DDK (Flag)
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
