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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1622-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human P2Y13 / P2RY13 Antibody (Cytoplasmic Domain, IHC) LS‑A1622
PathPlus™ Polyclonal Rabbit anti‑Human P2Y13 / P2RY13 Antibody (Cytoplasmic Domain, IHC) LS‑A1622
Antibody:
P2Y13 / P2RY13 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
P2Y13 / P2RY13 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Purinergic receptor P2Y, G-protein coupled, 13 (P2RY13) is a receptor for ADP. Coupled to G(i)-proteins. The P2Y13 receptor is versatile in its signaling; not only can it couple to different G proteins (Gs/Gq) but it can also trigger intracellular pathways related to the activation of MAPKs (mitogen-activated protein kinases) and the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3 axis. It is implicated in the regulation of cholesterol and glucose metabolism, bone homeostasis and aspects of central nervous system function such as pain transmission and neuroprotection.
References: Plos One doi.org/10.1371/journal.pone.0095807; Advances in Experimental Medicine and Biology [01 Jan 2017, 1051:139-168]
Target
Human P2Y13 / P2RY13
Synonyms
P2RY13 | FKSG77 | G-protein coupled receptor 94 | GPR94 | G-protein coupled receptor 86 | GPCR1 | GPR86 | p2RY13 | SP174 | G protein-coupled receptor 86 | p2Y purinoceptor 13 | p2Y13
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Bat, Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human P2RY13 / P2Y13. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bovine, Bat (94%); Dog, Pig (81%).
Epitope
Cytoplasmic Domain
Specificity
Human P2RY13 / P2Y13. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PRPF4B (50%).
Applications
- IHC
- IHC - Paraffin (20 - 40 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About P2Y13 / P2RY13
Validation
Brain, substantia nigra
Brain, substantia nigra
Breast, adenocarcinoma
Breast, adenocarcinoma
Brain, choroid plexus
Brain, choroid plexus
Anti-P2Y13 / P2RY13 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2Y13 / P2RY13 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY13 / P2Y13 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY13 / P2Y13 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ P2Y13 / P2RY13 Antibody (Cytoplasmic Domain) for IHC LS-A1622 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Distinct P2Y Receptors Mediate Extension and Retraction of Microglial Processes in Epileptic and Peritumoral Human Tissue. Giampaolo Milior, Mélanie Morin-Brureau, Farah Chali, Caroline Le Duigou, Etienne Savary, Gilles Huberfeld, Nathalie Rouach, Johan Pallud, Laurent Capelle, Vincent Navarro, Bertrand Mathon, Stéphane Clemenceau, Richard Miles. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2020 February;40:1373-1388.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Mouse
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Bovine, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat
Applications:
ICC, Immunofluorescence, Western blot, Immunoprecipitation
Species:
Human
Applications:
Western blot, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
