Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (800) 227-6666
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-A1922-50 | 50 µg (1 mg/ml) | $440 |
1 of 3
2 of 3
3 of 3
PathPlus™ Polyclonal Rabbit anti‑Human QRFPR / GPR103 Antibody (Cytoplasmic Domain, IHC) LS‑A1922
PathPlus™ Polyclonal Rabbit anti‑Human QRFPR / GPR103 Antibody (Cytoplasmic Domain, IHC) LS‑A1922
Antibody:
QRFPR / GPR103 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
QRFPR / GPR103 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Pyroglutamylated RFamide peptide receptor (QRFPR, GPR103) is a G-protein coupled receptor that binds neuropeptides such as P518 (and the longer form, QRFP) in the brain. It is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels, and it regulates adrenal function via QRFP/P518. In immunohistochemistry, it has membranous and cytoplasmic positivity in the hypothalamus, kidney, thyroid, reproductive tissues, and pancreas and has lower levels of expression in a few other tissues.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human QRFPR / GPR103
Synonyms
QRFPR | AQ27 | G protein-coupled receptor 103 | QRFP receptor | SP9155 | G-protein coupled receptor 103 | GPR103
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from the C-Terminus cytoplasmic domain of human QRFPR / GPR103. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey, Marmoset (95%); Dog (85%); Horse, Rabbit (80%).
Epitope
Cytoplasmic Domain
Specificity
Human QRFPR / GPR103. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About QRFPR / GPR103
Validation
Brain, Hypothalamus, PVN
Brain, Hypothalamus, PVN
Brain, Accessory Nucleus
Brain, Accessory Nucleus
Anti-QRFPR / GPR103 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-QRFPR / GPR103 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ QRFPR / GPR103 Antibody (Cytoplasmic Domain) for IHC LS-A1922 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Bovine, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/3/2024
Date Requested: 11/3/2024
