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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1742-50 | 50 µg (1 mg/ml) | $440 |
1 of 3
2 of 3
3 of 3
PathPlus™ Polyclonal Rabbit anti‑Human RXFP3 Antibody (Cytoplasmic Domain, IHC) LS‑A1742
PathPlus™ Polyclonal Rabbit anti‑Human RXFP3 Antibody (Cytoplasmic Domain, IHC) LS‑A1742
Antibody:
RXFP3 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Rat, Hamster
Format:
Unconjugated, Unmodified
Overview
Antibody:
RXFP3 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Rat, Hamster
Format:
Unconjugated, Unmodified
Specifications
Description
GPR135 (RXFP3) is the receptor for RLN3/relaxin-3. Relaxin-3 is a member of a family of insulin-like hormones expressed in the brain and play roles in memory, stress, and appetite regulation. Binding of the ligand inhibits cAMP accumulation. It is expressed in tissues such as the adrenal, pituitary, pancreas, and regions of the brain.
Target
Human RXFP3
Synonyms
RXFP3 | GPCR135 | Relaxin-3 receptor 1 | Relaxin 3 receptor 1 | RXFPR3 | RLN3R1 | SALPR | RLN3 receptor 1
Host
Rabbit
Reactivity
Human, Rat, Hamster
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Bovine, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from 2nd cytoplasmic domain of human RXFP3. Percent identity with other species by BLAST analysis: Human, Gorilla, Marmoset, Rat, Hamster (100%); Monkey, Mouse, Bovine, Panda, Pig (95%); Rabbit, Opossum (80%).
Epitope
Cytoplasmic Domain
Specificity
Human RXFP3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except VGLL4 (45%).
Applications
- IHC
- IHC - Paraffin (14 - 28 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About RXFP3
Validation
Brain, substantia nigra
Brain, substantia nigra
Anti-RXFP3 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP3 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ RXFP3 Antibody (Cytoplasmic Domain) for IHC LS-A1742 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
