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PathPlusTM ER Alpha / Estrogen Receptor Antibodies
ER (Estrogen receptor / ESR1) is a biomarker that is prognostic for breast cancer and predicts response to hormonal therapy. Estrogen receptor is a nuclear hormone receptor with nuclear staining in malignant breast cancer cells, and usually has higher levels of expression in Luminal A subtypes compared to others (Jeselsohn, 2015). Levels of expression of estrogen receptor are used in conjunction with progesterone receptor (PR), HER2 and Ki-67 expression levels to subtype breast cancers for different downstream treatments. Most breast cancers have positive expression of ER protein, primarily in luminal tissues where the luminal A subtype sees high levels of expression. Staining for this target is expected to be nuclear. References: Nature reviews. Clinical oncology 2015 Jan; 12.1; 573-583, PMID: 26122181; World Journal of Clinical Oncology 2014 Aug; 5.3; 412-424, PMID:25114856;

3 PathPlusTM Antibodies
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Antibodies (3)
Primary (3)
ER Alpha / Estrogen Receptor (3)
Human (2)
IHC (1)
IHC-P (3)
WB (1)
ICC (1)
rabbit (2)
mouse (1)
Product Group
Antibodies to Coronavirus-Associated Targets (3)
PathPlus Cancer (3)
PathPlus Cancer Pathology (3)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (2)
6F11 (1)
Unconjugated (3)
C-Terminus (1)
No (2)
Yes (1)
ER Alpha / Estrogen Receptor Antibody - Human Breast, Carcinoma: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
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ER Alpha / Estrogen Receptor Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
ER Alpha / Estrogen Receptor Antibody - Anti-Estrogen Receptor antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer Pathology
Cancer
ER Alpha / Estrogen Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ICC, IHC-P
Unconjugated
50 µl/$485
ER Alpha / Estrogen Receptor Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
ER Alpha / Estrogen Receptor Mouse anti-Human Monoclonal (6F11) Antibody
Human
IHC, IHC-P, WB
Unconjugated
1 ml/$1,185
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