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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Estrogen-related receptor alpha (ESRRA) regulates the promoters of lactoferrin, medium-chain acyl CoA dehydrogenase, osteopontin, and thyroid receptor alpha, and it may affect cellular energy balance and bone formation. ESRRA binds as a monodimer to the extended half-site TNAAGGTCA and as a homodimer to the estrogen response element (ERE). It is a constitutive activator of the estrogen response element and the palindromic thyroid hormone response element (TRE) but not of the glucocorticoid response element (GRE).
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804