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FOLR1 / Folate Receptor Alpha
folate receptor 1 (adult)
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
| Gene Name: | folate receptor 1 (adult) |
| Synonyms: | FOLR1, Adult folate-binding protein, FBP, Folate receptor alpha, KB cells FBP, Folate binding protein, Folate receptor 1, Folate receptor 1 (adult), Folate receptor, adult, FOLR, FR-alpha |
| Target Sequences: | NM_016730 NP_057942.1 P15328 |
Publications (6)
1
A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy. Liang X, Luo M, Wei XW, Ma CC, Yang YH, Shao B, Liu YT, Liu T, Ren J, Liu L, He ZY, Wei YQ. Oncotarget. 2016 7:52207-52217. (Flo; Mouse)
[Full Text Article]
[PubMed:27438147]
[PMC:PMC5239545]
Related Antibodies: LS-B5727.
2
Expression status of folate receptor alpha is a predictor of survival in pancreatic ductal adenocarcinoma. Cai L, Michelakos T, Ferrone CR, Zhang L, Deshpande V, Shen Q, DeLeo A, Yamada T, Zhang G, Ferrone S, Wang X. Oncotarget. 2017 8:37646-37656. (IHC, Flo; Human)
[Full Text Article]
[PubMed:28430580]
[PMC:PMC5514937]
Related Antibodies: LS-B5727, LS-C129132.
3
Intraoperative near-infrared fluorescence imaging targeting folate receptors identifies lung cancer in a large-animal model. Keating JJ, Runge JJ, Singhal S, Nims S, Venegas O, Durham AC, Swain G, Nie S, Low PS, Holt DE. Cancer. 2017 May;123:1051-1060. [Full Text Article]
[PubMed:28263385]
[PMC:PMC5341137]
Related Antibodies: LS-B5727.
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(108)
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(2)
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(1)
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(4)
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Low endotoxin level
(7)
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (aa179-228) (HRP) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (aa179-228) (Biotin) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (aa179-228) (FITC) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (aa25-234) Antibody
Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
FOLR1 / Folate Receptor Alpha Mouse anti-Human Monoclonal (aa25-233) (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$890
FOLR1 / Folate Receptor Alpha Mouse anti-Human Monoclonal (aa25-233) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$962
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Sandwich
96-Well Microplate
Human
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Breast Milk, Cell Culture Supernatants, Plasma, Saliva, Serum, Urine
1 Plate/$699
Sandwich
12 x 8-Well Microstrips
Human
94 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$534
Sandwich CLIA
96-Well Strip Plate
Human
1.37 - 1000 pg/ml
Chemiluminescent
Plasma, Serum, Tissue Homogenates
1 Plate/$851
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (aa41-90) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
FOLR1 / Folate Receptor Alpha Mouse anti-Bovine Monoclonal (SF55 (BGN/1210/55)) Antibody
Bovine
ELISA
Unconjugated
0.2 mg/$486
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, IHC-P, IP, WB
Unconjugated, Preservative Free
50 µl/$317; 100 µl/$375; 200 µl/$473
FOLR1 / Folate Receptor Alpha Mouse anti-Human Monoclonal (3G12B7) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
FOLR1 / Folate Receptor Alpha Mouse anti-Human Monoclonal (Preservative Free) (06) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$256; 100 µl/$412
FOLR1 / Folate Receptor Alpha Mouse anti-Human Monoclonal (2G5C12) Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µl/$459
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (Tyr80) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$391
FOLR1 / Folate Receptor Alpha Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IP, WB
Unconjugated
100 µl/$299
FOLR1 / Folate Receptor Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
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