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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137391-10 | 10 µg | $303 |
| LS-G137391-50 | 50 µg | $453 |
| LS-G137391-500 | 500 µg | $1,987 |
| LS-G137391-1 | 1 mg | $2,837 |
Human IL23R Protein (Recombinant Fc, C-terminus) - LS-G137391
Human IL23R Protein (Recombinant Fc, C-terminus) - LS-G137391
Description:
IL23R Protein LS-G137391 is a Recombinant Human IL23R produced in Mammalian Cells 24-353aa with Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
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Overview
Description:
IL23R Protein LS-G137391 is a Recombinant Human IL23R produced in Mammalian Cells 24-353aa with Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
IL23R
Synonyms
IL23R | IL-23 receptor | Interleukin 23 receptor | IBD17 | IL-23R | Interleukin-23 receptor
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
Fc, C-terminus
Region
24-353aa
Predicted Molecular Weight
65 kDa
AA Sequence
GITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQPRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGD
Expression System
Mammalian Cells
Source Species
Mammal
Purification
Greater than 90% by SDS-PAGE
Usage Summary
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Bio-Activity
The ED50 as determined by its ability to binding recombinant human IL-23A&IL12B used funtional ELISA is less than 5 ug/ml.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 0.2 µm filtered PBS, pH 7.4
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About IL23R
Publications (0)
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular IL23R Proteins
Source:
Human
Tag:
Fc, C-terminus
Source:
Human
Tag:
6His, C-terminus
Source:
Hamster-Chinese
Tag:
Human IgG1 Fc
Source:
Mammal
Tag:
Fc, C-terminus
Source:
Human
Tag:
Fc, C-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
