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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137411-10 | 10 µg | $250 |
| LS-G137411-50 | 50 µg | $327 |
| LS-G137411-500 | 500 µg | $1,170 |
| LS-G137411-1 | 1 mg | $1,518 |
Human TRAIL-R3 / DCR1 Protein (Recombinant 6His, C-terminus) - LS-G137411
Human TRAIL-R3 / DCR1 Protein (Recombinant 6His, C-terminus) - LS-G137411
Description:
TRAIL-R3 / DCR1 Protein LS-G137411 is a Recombinant Human TRAIL-R3 / DCR1 produced in Mammalian Cells 26-221aa with 6His, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Description:
TRAIL-R3 / DCR1 Protein LS-G137411 is a Recombinant Human TRAIL-R3 / DCR1 produced in Mammalian Cells 26-221aa with 6His, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
TRAIL-R3 / DCR1
Synonyms
TNFRSF10C | CD263 antigen | CD263 | Cytotoxic TRAIL receptor-3 | Decoy receptor 1 | DCR1 | DCR1-TNFR | LIT | Lymphocyte inhibitor of TRAIL | TRAIL-R3 | TRAILR3 | TRAIL receptor 3 | TRID
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
6His, C-terminus
Region
26-221aa
Predicted Molecular Weight
21.78 kDa
AA Sequence
ATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRCPSGEVQVSNCTSWDDIQCVEEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETMTTSPGTPA
Expression System
Mammalian Cells
Source Species
Mammal
Purification
Greater than 95% by SDS-PAGE
Usage Summary
Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Bio-Activity
The ED50 as determined by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL is less than 200 ng/ml.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 0.2 µm filtered 20 mM PBs, pH 7.2, 150 mM NaCl
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TRAIL-R3 / DCR1
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/28/2024
Date Requested: 11/28/2024
