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A2M / Alpha-2-Macroglobulin

alpha-2-macroglobulin

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Gene Name: alpha-2-macroglobulin
Synonyms: A2M, CPAMD5, A2MD, FWP007, Alpha-2-M, Alpha-2-macroglobulin, S863-7
Target Sequences: NM_000014 NP_000005.2 P01023

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Products
ELISA Kits (27)
Competitive EIA (3)
Custom (2)
Development Kit (1)
Sandwich (19)
Sandwich CLIA (2)
A2M / Alpha-2-Macroglobulin (27)
Human (12)
Mouse (2)
Rat (5)
Bovine (2)
Chicken (1)
Monkey (2)
Rabbit (2)
Rhesus monkey (1)
Product Group
DevKit DuoPlus (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (3)
96-Well Strip Plate (22)
Antibody Pair and Standard (1)
No (27)
Biological Fluids (1)
Cell Culture Supernatants (6)
Cell Lysates (2)
Cell Supernatant (1)
Plasma (25)
Serum (25)
Tissue Homogenates (10)
Urine (4)
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
625 - 40000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
A2M / Alpha-2-Macroglobulin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$757
A2M / Alpha-2-Macroglobulin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
6.17 - 500 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Urine
1 Plate/$617
A2M / Alpha-2-Macroglobulin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Biological Fluids, Plasma, Serum, Tissue Homogenates
1 Plate/$585
A2M / Alpha-2-Macroglobulin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
A2M / Alpha-2-Macroglobulin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
9.38 - 600 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
A2M / Alpha-2-Macroglobulin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Urine
1 Plate/$685
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
0.156 - 10 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
A2M / Alpha-2-Macroglobulin ELISA Kit
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Sandwich
96-Well Microplate
Human
12.29 - 1200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
A2M / Alpha-2-Macroglobulin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
1.25 - 20 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$822
A2M / Alpha-2-Macroglobulin ELISA Kit
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Sandwich
96-Well Strip Plate
Rhesus monkey
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$826
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
3.13 - 800 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$1,002
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 ng/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$528
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
123.5 - 10000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Urine
500 Wells/$1,089; 1000 Wells/$1,589
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$585
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
0.14 - 100 ng/ml
Chemiluminescent
Plasma, Serum, Urine
1 Plate/$851
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
625 - 40000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78.125 - 5000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
A2M / Alpha-2-Macroglobulin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
Viewing 1-25 of 27 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).