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AADAC

arylacetamide deacetylase

Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.

Gene Name: arylacetamide deacetylase
Synonyms: AADAC, CES5A1, DAC, Arylacetamide deacetylase
Target Sequences: NM_001086 NP_001077.2 P22760

Publications (1)

1
Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes. Mallanna SK, Cayo MA, Twaroski K, Gundry RL, Duncan SA. Stem cell reports. 2016 7:543-556. (WB; Human) [Full Text Article] [PubMed:27569060] [PMC:PMC5032032] Related Antibodies: LS-C155827.

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
AADAC (6)
No (6)
10His-SUMO, N-terminus + Myc, C-terminus (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
AADAC Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-SUMO, N-terminus + Myc, C-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
AADAC Protein - 12.5% SDS-PAGE of human AADAC stained with Coomassie Blue
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Wheat Germ Extract
GST
72.1 kDa
2 µg/$439
AADAC Protein - Purified recombinant protein AADAC was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.6 kDa
20 µg/$1,107
AADAC Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
AADAC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.6 kDa
20 µg/$150
AADAC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.6 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).