AANAT

aralkylamine N-acetyltransferase

AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

AANAT (6)

Publications

No (6)

Tag

10His-GST, N-terminus (1)

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (2)

Species

Human (3)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human AANAT Protein (Recombinant GST, N-terminus) (aa1-79) - LS-G57662

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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AANAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119914

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.2 kDa

Price:

100 µg/$494

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Human AANAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78782

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.2 kDa

Price:

20 µg/$150

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Human AANAT Protein (Recombinant 10His-GST, N-terminus) (Full Length) - LS-G137348

Source:

E. coli

Tag:

10His-GST, N-terminus

Molecular Weight:

51.8 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Mouse AANAT Protein (Recombinant His-T7) (Glu22-Lys236) - LS-G24562

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.4 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,441

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Rat AANAT Protein (Recombinant His-T7) (aa22-235) - LS-G24563

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.2 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,601

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