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AARS

alanyl-tRNA synthetase

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

Gene Name: alanyl-tRNA synthetase
Synonyms: AARS, AlaRS, CMT2N, Alanyl-tRNA synthetase
Target Sequences: NM_001605 NP_001596.2 P49588

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
AARS (5)
No (5)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (3)
Mouse (1)
293T Cells (1)
Baculovirus (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (1)
AARS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
106.6 kDa
100 µg/$494
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Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
108.3 kDa
100 µg/$721
AARS Protein - 12.5% SDS-PAGE of human AARS stained with Coomassie Blue
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Wheat Germ Extract
GST
133.2 kDa
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
106.6 kDa
20 µg/$150
AARS Protein - Purified recombinant protein AARS was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
106.6 kDa
20 µg/$1,107
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).