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ABCA7

ATP-binding cassette, sub-family A (ABC1), member 7

ABCA7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.

Gene Name: ATP-binding cassette, sub-family A (ABC1), member 7
Family/Subfamily: Transporter , ATP-binding cassette - ABCA/ABC1
Synonyms: ABCA7, ABCA-SSN, Autoantigen SS-N, ABCX, Macrophage ABC transporter
Target Sequences: NM_019112 NP_061985.2 Q8IZY2

Publications (3)

1
Expression, localization, and functional model of cholesterol transporters in lactating and nonlactating mammary tissues of murine, bovine, and human origin. Mani O, Krner M, Sorensen MT, Sejrsen K, Wotzkow C, Ontsouka CE, Friis RR, Bruckmaier RM, Albrecht C. American journal of physiology. Regulatory, integrative and comparative physiology. 2010 299:R642-54. (IHC-P; Mouse, Bovine, Human) [PubMed:20445153]
2
ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content. Nowyhed HN, Chandra S, Kiosses W, Marcovecchio P, Andary F, Zhao M, Fitzgerald ML, Kronenberg M, Hedrick CC. Scientific reports. 2017 7:40273. (WB; Mouse) [Full Text Article] [PubMed:28091533] [PMC:PMC5238393]
3
ABCA7 loss-of-function variants, expression, and neurologic disease risk. Allen M, Lincoln SJ, Corda M, Watzlawik JO, Carrasquillo MM, Reddy JS, Burgess JD, Nguyen T, Malphrus K, Petersen RC, Graff-Radford NR, Dickson DW, Ertekin-Taner N. Neurology. Genetics. 2017 January;3:e126. (Human) [Full Text Article] [PubMed:28097223] [PMC:PMC5217615]

☰ Filters
Products
Antibodies (17)
Primary (17)
ABCA7 (17)
Human (10)
Mouse (9)
Rat (3)
IHC (9)
IHC-P (5)
WB (16)
Flo (5)
ELISA (2)
Peptide-ELISA (1)
rabbit (7)
rabbit-new zealand white (5)
rat (5)
Product Group
PathPlus Cancer (1)
IgG (2)
IgG2a,k (5)
monoclonal mc (5)
polyclonal pc (12)
7A1-144 (5)
Biotin Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
Unconjugated (13)
C-Terminus (1)
aa1050-1100 (1)
aa2070-2120 (1)
aa2100-2146 (1)
aa2100-2155 (1)
aa440-490 (1)
aa60-110 (1)
No (17)
ABCA7 Antibody - Detection of ABCA7 using ABCA7, mouse antibody at various dilutions in ABCA7 transfected HeLa cell lysates.
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ABCA7 Rat anti-Mouse Monoclonal (7A1-144) Antibody
Mouse
Flo, WB
Unconjugated
0.1 ml/$386
ABCA7 Antibody - Western blot of ABCA7 antibody at 1:500 dilution. Lane 1: LO2 whole cell lysate. Lane 2: sp20 whole cell lysate. Lane 3: H9C2 whole cell lysate.
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ABCA7 Rabbit anti-Human Polyclonal (aa2070-2120) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
ABCA7 Antibody - Western blot analysis of ABCA7 expression in HeLa (A); Raw264.7 (B); mouse liver (C); PC12 (D) whole cell lysates.
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ABCA7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
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ABCA7 Rabbit-New Zealand White anti-Mouse Polyclonal (aa2100-2155) Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$393
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ABCA7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
ABCA7 Antibody - Anti-ABCA7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCA7 Rat anti-Mouse Monoclonal (Biotin) (7A1-144) Antibody
Mouse
Flo, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
ABCA7 Antibody - Anti-ABCA7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCA7 Rat anti-Mouse Monoclonal (DY488) (7A1-144) Antibody
Mouse
Flo, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
ABCA7 Antibody - Anti-ABCA7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCA7 Rat anti-Mouse Monoclonal (DY550) (7A1-144) Antibody
Mouse
Flo, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
ABCA7 Antibody - Anti-ABCA7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCA7 Rat anti-Mouse Monoclonal (DY650) (7A1-144) Antibody
Mouse
Flo, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
ABCA7 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
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ABCA7 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
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ABCA7 Rabbit-New Zealand White anti-Human Polyclonal (aa60-110) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
Select
ABCA7 Rabbit-New Zealand White anti-Human Polyclonal (aa1050-1100) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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ABCA7 Rabbit-New Zealand White anti-Human Polyclonal (aa2100-2146) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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ABCA7 Rabbit-New Zealand White anti-Human Polyclonal (aa440-490) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
Select
ABCA7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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ABCA7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
ABCA7 Antibody - Western blot analysis of ABCA7 using Jurkat whole cells lysates
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ABCA7 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).