ABCB1 / MDR1 / P Glycoprotein

ATP-binding cassette, sub-family B (MDR/TAP), member 1

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

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Products

Proteins (9)

Type

Recombinant (9)

Target

ABCB1 / MDR1 / P Glycoprotein (9)

Publications

No (9)

Tag

DDK,C-terminus (1)

GST, N-terminus (1)

His (3)

His,C-terminus (1)

His-GST (1)

His-GST, N-terminus (1)

His-SUMO (1)

Species

Entamoeba histolytica (1)

Human (4)

Mouse (2)

Plasmodium falciparum (2)

Source

E. coli (4)

Sf9 Cells (2)

Wheat Germ Extract (1)

Yeast (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human ABCB1 / MDR1 / P Glycoprotein (Recombinant His-GST, N-terminus) (Phe394-Val672) - LS-G14152

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

57.9 kDa

Price:

10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430

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Human ABCB1 / MDR1 / P Glycoprotein (Recombinant His,C-terminus) - LS-G142372

Source:

Sf9 Cells

Tag:

His,C-terminus

Molecular Weight:

41 kDa

Price:

20 µg/$677

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Mouse ABCB1 / MDR1 / P Glycoprotein (Recombinant His-GST) (Leu391-Thr627) - LS-G14155

Source:

E. coli

Tag:

His-GST

Molecular Weight:

57.9 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Human ABCB1 / MDR1 / P Glycoprotein (Recombinant GST, N-terminus) (aa620-709) - LS-G59585

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse ABCB1 / MDR1 / P Glycoprotein (Recombinant His) (aa994-1276) - LS-G141024

Source:

E. coli

Sequence Length:

282 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

31.13 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Human ABCB1 / MDR1 / P Glycoprotein (Recombinant DDK,C-terminus) - LS-G142373

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

31.3 kDa

Price:

20 µg/$677

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Plasmodium falciparum ABCB1 / MDR1 / P Glycoprotein (Recombinant His-SUMO) (aa1084-1419) - LS-G21389

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

54.17 kD

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Plasmodium falciparum ABCB1 / MDR1 / P Glycoprotein (Recombinant His) (aa1084-1419) - LS-G23229

Source:

Yeast

Tag:

His

Molecular Weight:

40.19 kD

Price:

100 µg/$679; 20 µg/$429; 1 mg/$1,973

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Entamoeba histolytica ABCB1 / MDR1 / P Glycoprotein (Recombinant His) (Full Length) - LS-G22775

Source:

Yeast

Tag:

His

Molecular Weight:

14.49 kD

Price:

1 mg/$1,973; 100 µg/$679; 20 µg/$429

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