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ABCB11 / BSEP

ATP-binding cassette, sub-family B (MDR/TAP), member 11

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Family/Subfamily: Transporter , ATP-binding cassette - ABCB/MDR
Synonyms: ABCB11, ABC16, Bile salt export pump, BSEP, PGY4, Sister p-glycoprotein, BRIC2, PFIC-2, PFIC2, SPGP
Target Sequences: NM_003742 NP_003733.2 O95342

Publications (1)

1
Anticholestatic Effect of Bardoxolone Methyl on Hepatic Ischemia-reperfusion Injury in Rats. Joohyun Kim, Catherine E Hagen, Suresh N Kumar, Jong-In Park, Michael A Zimmerman, Johnny C Hong. Transplantation direct. 2020 August;6:e584. [Full Text Article] [PubMed:32766432] [PMC:PMC7371100] Related Antibodies: LS-C490094.

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Products
Antibodies (32)
Primary (32)
ABCB11 / BSEP (32)
Human (23)
Mouse (16)
Rat (3)
IHC (8)
IHC-P (7)
WB (27)
Flo (1)
ELISA (3)
ICC (2)
IF (1)
Peptide-ELISA (1)
rabbit (27)
mouse (5)
Product Group
IHCPlus (3)
IgG (6)
IgG1 (5)
monoclonal mc (5)
polyclonal pc (27)
AHC0021 (1)
G518.1 (1)
APC (2)
APC Conjugated (2)
Biotin Conjugated (2)
Concentrated (1)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Ready-to-Use (1)
Unconjugated (18)
aa420-656 (8)
aa421-663 (8)
aa1038-1067 (2)
aa1063-1097 (1)
aa705-718 (1)
No (31)
Yes (1)
ABCB11 / BSEP Antibody - Anti-ABCB11 / BSEP antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ABCB11 / BSEP Mouse anti-Human Monoclonal (aa705-718) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$485
ABCB11 / BSEP Antibody
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ABCB11 / BSEP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
ABCB11 / BSEP Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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ABCB11 / BSEP Rabbit anti-Human Polyclonal (aa1038-1067) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$358
ABCB11 / BSEP Antibody - Western blot blot of extracts of various cells, using ABCB11 antibody.
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ABCB11 / BSEP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ABCB11 / BSEP Antibody - Immunohistochemistry - Anti-ABCB11/Bsep Picoband Antibody
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ABCB11 / BSEP Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ABCB11 / BSEP Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ABCB11 / BSEP Mouse anti-Human Monoclonal (Concentrated) Antibody
Human
ELISA, IHC-P
Unconjugated, Concentrated
0.05 ml/$460
ABCB11 / BSEP Antibody
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ABCB11 / BSEP Mouse anti-Human Monoclonal (Ready-to-Use) Antibody
Human
ELISA, IHC-P
Unconjugated, Ready-to-Use
7 ml/$424
ABCB11 / BSEP Antibody - Anti-ABCB11 Antibody (C-term) at 1:2000 dilution + mouse liver lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 146 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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ABCB11 / BSEP Rabbit anti-Human Polyclonal (aa1063-1097) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
200 µl/$393
ABCB11 / BSEP Antibody - Western blot of recombinant ABCB11 / BSEP.
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ABCB11 / BSEP Rabbit anti-Mouse Polyclonal (aa420-656) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
ABCB11 / BSEP Antibody - Western blot of recombinant ABCB11 / BSEP.
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ABCB11 / BSEP Rabbit anti-Mouse Polyclonal (aa420-656) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
ABCB11 / BSEP Antibody - Western blot of recombinant ABCB11 / BSEP.
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ABCB11 / BSEP Rabbit anti-Mouse Polyclonal (aa420-656) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
ABCB11 / BSEP Antibody - Western blot of recombinant ABCB11 / BSEP.
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ABCB11 / BSEP Rabbit anti-Mouse Polyclonal (aa420-656) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
ABCB11 / BSEP Antibody - Western blot of recombinant ABCB11 / BSEP.
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ABCB11 / BSEP Rabbit anti-Mouse Polyclonal (aa420-656) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
ABCB11 / BSEP Antibody - Western blot of recombinant ABCB11 / BSEP.
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ABCB11 / BSEP Rabbit anti-Mouse Polyclonal (aa420-656) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
ABCB11 / BSEP Antibody - Western blot of recombinant ABCB11 / BSEP.
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ABCB11 / BSEP Rabbit anti-Mouse Polyclonal (aa420-656) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
ABCB11 / BSEP Antibody - Western blot of recombinant ABCB11 / BSEP.
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ABCB11 / BSEP Rabbit anti-Mouse Polyclonal (aa420-656) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
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ABCB11 / BSEP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ABCB11 / BSEP Antibody
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ABCB11 / BSEP Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
ABCB11 / BSEP Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ABCB11 / BSEP Rabbit anti-Human Polyclonal (aa421-663) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
ABCB11 / BSEP Rabbit anti-Human Polyclonal (aa1038-1067) Antibody
Mouse, Human
IHC, WB
Unconjugated
200 µl/$734
Select
ABCB11 / BSEP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
ABCB11 / BSEP Mouse anti-Human Monoclonal (G518.1) Antibody
Human
IHC
Unconjugated
100 µl/$427
ABCB11 / BSEP Antibody - Stained on Human Liver Tissue
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ABCB11 / BSEP Mouse anti-Human Monoclonal (AHC0021) Antibody
Human
IHC
Unconjugated
0.1 ml/$342
ABCB11 / BSEP Antibody - Immunofluorescence analysis of C6 cells using ABCB11 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
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ABCB11 / BSEP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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ABCB11 / BSEP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).