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ABCB5

ATP-binding cassette, sub-family B (MDR/TAP), member 5

Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.

Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Family/Subfamily: Transporter , ATP-binding cassette - ABCB/MDR
Synonyms: ABCB5, ABCB5alpha, ABCB5 P-gp, ABCB5beta, ATP-binding cassette protein, EST422562, P-glycoprotein ABCB5
Target Sequences: NM_178559 NP_848654.3 Q2M3G0

Publications (2)

1
Evaluation of a multi-marker immunomagnetic enrichment assay for the quantification of circulating melanoma cells. Freeman JB, Gray ES, Millward M, Pearce R, Ziman M. Journal of translational medicine. 2012 10:192. [PubMed:22978632] [PMC:PMC3480925] Related Antibodies: LS-B3454.
2
Targeting melanoma stem cells with the Vitamin E derivative d-tocotrienol. Marzagalli M, Moretti RM, Messi E, Marelli MM, Fontana F, Anastasia A, Bani MR, Beretta G, Limonta P. Scientific reports. 2018 8:587. (ICC; Human) [Full Text Article] [PubMed:29330434]

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Products
Antibodies (36)
Primary (36)
ABCB5 (36)
Human (36)
Mouse (7)
Rat (1)
Monkey (1)
IHC (14)
IHC-P (11)
WB (22)
Flo (2)
ELISA (8)
ICC (10)
IF (1)
Peptide-ELISA (2)
rabbit (29)
mouse (4)
goat (2)
sheep (1)
Product Group
IHCPlus (2)
IgG (13)
IgG1 (1)
monoclonal mc (4)
polyclonal pc (32)
11A2 (2)
7L3 (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (18)
aa570-808 (8)
Internal (2)
aa1-30 (1)
aa141-247 (1)
aa905-916 (1)
No (35)
Yes (1)
ABCB5 Antibody - Anti-ABCB5 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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ABCB5 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
ABCB5 Antibody - Anti-ABCB5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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ABCB5 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ABCB5 Antibody - IHC - ABCB5 Antibody. Immunohistochemistry of ABCB5 antibody tissue: human liver Fixation: formalin fixed paraffin embedded Antigen retrieval: user optimized Primary antibody: ABCB5 1:200 Secondary antibody: Peroxidase goat anti-rabbit at 1:10000 for 45 min at RT Localization: Moderate to strong cytoplasmic and membranous staining was observed in hepatocytes. Occasional nuclear staining was observed in hepatocytes and sinusoidal cells. Staining: antibody as precipitated red signal with a hematoxylin purple nuclear counterstain.
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ABCB5 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$567
ABCB5 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using antibody at dilution of 1:100.
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ABCB5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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ABCB5 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
50 µg/$294; 100 µg/$360
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ABCB5 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
50 µg/$294; 100 µg/$360
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ABCB5 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
50 µg/$294; 100 µg/$360
ABCB5 Antibody - Antibody (0.03 ug/ml) staining of A431 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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ABCB5 Goat anti-Human Polyclonal (aa905-916) Antibody
Human
Flo, Peptide-ELISA, WB
Unconjugated
100 µg/$503
ABCB5 Antibody - Western blot of ABCB5 antibody.
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ABCB5 Rabbit anti-Human Polyclonal (aa570-808) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
ABCB5 Antibody - Western blot of ABCB5 antibody.
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ABCB5 Rabbit anti-Human Polyclonal (aa570-808) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
ABCB5 Antibody - Immunohistochemistry of rabbit anti ABCB5 antibody. Tissue: human breast carcinoma at pH6. Fixation: formalin fixed paraffin embedded. Primary antibody: ABCB5 antibody at 10 µg/mL for 1 h at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: ABCB5 is cytoplasmic. Staining: ABCB5 as precipitated brown signal with hematoxylin purple nuclear counterstain.
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ABCB5 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
25 µl/$304
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ABCB5 Mouse anti-Human Monoclonal (7L3) Antibody
Human
IF, IHC-P, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ABCB5 Antibody - Immunohistochemistry: ABCB5 Antibody - Analysis of ABCB5 in mouse spleen using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IHC, IHC-P
Unconjugated
0.1 ml/$386
ABCB5 Antibody - Immunohistochemistry: ABCB5 Antibody - Analysis of ABCB5 in mouse spleen using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB5 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ICC, IHC, IHC-P
Biotin Conjugated
0.1 ml/$416
ABCB5 Antibody - Immunohistochemistry: ABCB5 Antibody - Analysis of ABCB5 in mouse spleen using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB5 Rabbit anti-Human Polyclonal (DY488) Antibody
Mouse, Human
ICC, IHC, IHC-P
DY488 Conjugated
0.1 ml/$416
ABCB5 Antibody - Immunohistochemistry: ABCB5 Antibody - Analysis of ABCB5 in mouse spleen using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB5 Rabbit anti-Human Polyclonal (DY550) Antibody
Mouse, Human
ICC, IHC, IHC-P
DY550 Conjugated
0.1 ml/$416
ABCB5 Antibody - Immunohistochemistry: ABCB5 Antibody - Analysis of ABCB5 in mouse spleen using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB5 Rabbit anti-Human Polyclonal (DY650) Antibody
Mouse, Human
ICC, IHC, IHC-P
DY650 Conjugated
0.1 ml/$416
ABCB5 Antibody - Immunohistochemical analysis of ABCB5 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ABCB5 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
ABCB5 Antibody - Western blot analysis of 293T cell lysate  using ABCB5 Polyclonal Antibody at dilution of 1:500
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ABCB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ABCB5 Goat anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$558
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ABCB5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ABCB5 Antibody - Immunocytochemistry/Immunofluorescence: ABCB5 Antibody - ABCB5 antibody was tested in A431 cells with FITC (green). Nuclei were counterstained with DAPI (blue).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB5 Rabbit anti-Human Polyclonal Antibody
Human
ICC
Unconjugated
0.1 ml/$386
ABCB5 Antibody - Immunocytochemistry/Immunofluorescence: ABCB5 Antibody - ABCB5 antibody was tested in A431 cells with FITC (green). Nuclei were counterstained with DAPI (blue).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB5 Rabbit anti-Human Polyclonal (DY550) Antibody
Human
ICC
DY550 Conjugated
0.1 ml/$416
ABCB5 Antibody - Immunocytochemistry/Immunofluorescence: ABCB5 Antibody - ABCB5 antibody was tested in A431 cells with FITC (green). Nuclei were counterstained with DAPI (blue).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB5 Rabbit anti-Human Polyclonal (DY650) Antibody
Human
ICC
DY650 Conjugated
0.1 ml/$416
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ABCB5 Mouse anti-Human Monoclonal (11A2) Antibody
Human
WB
Unconjugated
100 µg/$357
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).