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ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
| Gene Name: | ATP-binding cassette, sub-family B (MDR/TAP), member 5 |
| Family/Subfamily: | Transporter , ATP-binding cassette - ABCB/MDR |
| Synonyms: | ABCB5, ABCB5alpha, ABCB5 P-gp, ABCB5beta, ATP-binding cassette protein, EST422562, P-glycoprotein ABCB5 |
| Target Sequences: | NM_178559 NP_848654.3 Q2M3G0 |
Publications (2)
1
Evaluation of a multi-marker immunomagnetic enrichment assay for the quantification of circulating melanoma cells. Freeman JB, Gray ES, Millward M, Pearce R, Ziman M. Journal of translational medicine. 2012 10:192.
[PubMed:22978632]
[PMC:PMC3480925]
Related Antibodies: LS-B3454.
2
Targeting melanoma stem cells with the Vitamin E derivative d-tocotrienol. Marzagalli M, Moretti RM, Messi E, Marelli MM, Fontana F, Anastasia A, Bani MR, Beretta G, Limonta P. Scientific reports. 2018 8:587. (ICC; Human)
[Full Text Article]
[PubMed:29330434]
☰ Filters
Products
Proteins
(3)
Type
Recombinant
(3)
Target
ABCB5
(3)
Publications
No
(3)
Tag
His-S
(1)
TRX, N-terminus
(2)
Species
Human
(3)
Source
E. coli
(3)
Purification
Purified
(1)
Low Endotoxin Level
Low endotoxin level
(2)
E. coli
TRX, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
29.4kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
E. coli
TRX, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
29.4 kDa
10 µg/$317; 50 µg/$524
E. coli
His-S
30.1 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
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