ABCB7

ATP-binding cassette, sub-family B (MDR/TAP), member 7

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ABCB7 (5)

Publications

No (5)

Tag

GST (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (2)

Species

Human (3)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ABCB7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88708

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.6 kDa

Price:

20 µg/$150

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ABCB7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116747

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.6 kDa

Price:

100 µg/$494

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Human ABCB7 Protein (Recombinant His-T7, N-terminus) (Val472-Cys752) - LS-G133271

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

34.7kDa

Price:

10 µg/$269; 50 µg/$362; 200 µg/$725; 100 µg/$580; 1 mg/$1,760; 500 µg/$1,330; 5 mg/$2,715; 2 mg/$1,940

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Mouse ABCB7 Protein (Recombinant His-T7, N-terminus) (Val472-Cys752) - LS-G133435

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

34.6kDa

Price:

10 µg/$273; 50 µg/$392; 200 µg/$785; 100 µg/$627; 1 mg/$1,852; 500 µg/$1,409; 5 mg/$2,814; 2 mg/$2,035

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Human ABCB7 Protein (Recombinant GST) (Full Length) - LS-G27315

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

104.39 kDa

Price:

2 µg/$439

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