ABCC11 / MRP8

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E217betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. Probably functions to secrete earwax.

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Products

Proteins (5)

Type

Recombinant (5)

Target

ABCC11 / MRP8 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His-GST, N-terminus (1)

His-T7 (1)

His-T7, N-terminus (1)

Species

Human (3)

Mouse (1)

Rat (1)

Source

E. coli (3)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human ABCC11 / MRP8 Protein (Recombinant GST) (Full Length) - LS-G35902

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

88.5 kDa

Price:

2 µg/$439

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Human ABCC11 / MRP8 Protein (Recombinant GST, N-terminus) (aa433-532) - LS-G63432

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Rat ABCC11 / MRP8 Protein (Recombinant His-GST, N-terminus) (Ile1127-Leu1366) - LS-G133257

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

56.7kDa

Price:

10 µg/$281; 50 µg/$442; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human ABCC11 / MRP8 Protein (Recombinant His-T7) (aa1141-1382) - LS-G25338

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.5 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Mouse ABCC11 / MRP8 Protein (Recombinant His-T7, N-terminus) (Ile1127-Leu1366) - LS-G133436

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

30.3kDa

Price:

10 µg/$267; 50 µg/$355; 200 µg/$710; 100 µg/$567; 1 mg/$1,735; 500 µg/$1,308; 5 mg/$2,687; 2 mg/$1,914

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