ABCC5 / MRP5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

ABCC5 / MRP5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear.

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Products

ELISA Kits (3)

Type

Sandwich (3)

Target

ABCC5 / MRP5 (3)

Reactivity

Human (3)

Format

96-Well Microplate (1)

96-Well Strip Plate (2)

Publications

No (3)

Sample Type

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

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Human ABCC5 / MRP5 (Sandwich ELISA) ELISA Kit - LS-F9508

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Human ABCC5 / MRP5 (Sandwich ELISA) ELISA Kit - LS-F24021

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human ABCC5 / MRP5 (Sandwich ELISA) ELISA Kit - LS-F33506

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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