ABHD12

Abhydrolase Domain Containing 12

ABHD12 is an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

ABHD12 (6)

Publications

No (6)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ABHD12 Protein (Recombinant GST) (Full Length) - LS-G33086

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72 kDa

Price:

2 µg/$439

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Human ABHD12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92592

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.4 kDa

Price:

20 µg/$150

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Human ABHD12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92590

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.9 kDa

Price:

20 µg/$150

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Human ABHD12 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72485

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.9 kDa

Price:

20 µg/$1,107

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ABHD12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113117

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.4 kDa

Price:

100 µg/$494

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ABHD12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119534

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.9 kDa

Price:

100 µg/$494

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