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May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.
Gene Name: | abl-interactor 2 |
Synonyms: | ABI2, Abelson interactor 2, Abl interactor 2, Abl-binding protein 3, ArgBP1, ArgBPIB, Arg-binding protein 1, Argbpib protein, ABI-2, ABI2B, Abl binding protein 3, Abl-interactor 2, Abl-interactor protein 2b, AblBP3, AIP-1, SSH3BP2, ArgBPIA |
Target Sequences: | NM_005759 NP_005750.4 Q9NYB9 |
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